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Mostrando ítems 11-20 de 102
Neuropsychological Study of Familial Alzheimer's Disease Caused by Mutation E280A in the Presenilin 1 Gene
(SAGE PublicationsGrupo de Neurociencias de AntioquiaWeston, Estados Unidos, 2023)
Presenilin-1 280Glu-->Ala mutation alters C-terminal APP processing yielding longer abeta peptides: implications for Alzheimer's disease
(Feinstein Institute for Medical Research, 2008-03)
Presenilin (PS) mutations enhance the production of the Abeta42 peptide that is derived from the amyloid precursor protein (APP). The pathway(s) by which the Abeta42 species is preferentially produced has not been elucidated, ...
Phosphorylated tau potentiates Aβ-induced mitochondrial damage in mature neurons
(Academic Press Inc., 2014)
Aspectos moleculares de la enfermedad de AlzheimerMolecular aspects of alzheimer's disease
(Universidad de Antioquia, Facultad de MedicinaMedellín, Colombia, 2021)
Identification of PSEN2 mutation p.N141I in Argentine pedigrees with early-onset familial Alzheimer's disease
(Elsevier Science Inc, 2015-10)
Presenilin 2 gene (PSEN2) mutations account for <5% of all early-onset familial Alzheimer's disease (EOFAD) cases and only 13 have strong evidence for pathogenicity. We aimed to investigate the presence of PSEN2 mutation ...