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Mostrando ítems 11-20 de 36
Leishmanicidal Effects of Piperlongumine (Piplartine) and Its Putative Metabolites
(George Thieme, 2018)
Overview of the therapeutic potential of piplartine (piperlongumine)
(Elsevier, 2013)
Synthetic Analogue Of The Natural Product Piperlongumine As A Potent Inhibitor Of Breast Cancer Cell Line Migration
(Soc Brasileira QuimicaSão Paulo, 2017)
Optimization of composition and obtainment parameters of biocompatible nanoemulsions intended for intraductal administration of piplartine (piperlongumine) and mammary tissue targeting
(Elsevier B.V., 2019-08-15)
As a new strategy for treatment of ductal carcinoma in situ, biocompatible and bioadhesive nanoemulsions for intraductal administration of the cytotoxic agent piplartine (piperlongumine) were optimized in this study. To ...
Estudo da interação da piplartina com albumina do soro humano por técnicas espectroscópicas
(Universidade Estadual Paulista (Unesp), 2017-03-24)
Piplartine is an alkaloid amide present in roots and stems of different peppers species of the genus Piper. This compound has several promising pharmacological properties, such as: antidepressant, anxiolytic, genotoxic, ...
Biological and physical approaches on the role of piplartine (piperlongumine) in cancer
(2020-12-01)
Chronic inflammation provides a favorable microenvironment for tumorigenesis, which opens opportunities for targeting cancer development and progression. Piplartine (PL) is a biologically active alkaloid from long peppers ...
Effect of piperlongumine during exposure to cigarette smoke reduces inflammation and lung injury
(2020-04-01)
Chronic obstructive pulmonary disease (COPD) is related to smoking and anti-inflammatory therapy is indicated. Among the mediators with anti-inflammatory properties, we highlight piperlongumine (PL), an alkaloid/amide of ...
Annexin a1 mimetic peptide and piperlongumine: Anti-inflammatory profiles in endotoxin-induced uveitis
(2021-11-01)
Uveitis is one of the main causes of blindness worldwide, and therapeutic alternatives are worthy of study. We investigated the effects of piperlongumine (PL) and/or annexin A1 (AnxA1) mimetic peptide Ac2-26 on endotoxin-induced ...
Protective effects of piperlongumin in the prevention of inflammatory damage caused by pulmonary exposure to benzopyrene carcinogen
(2021-01-01)
Benzopyrene is one of the main polycyclic aromatic hydrocarbons with carcinogenic capacity. Research has shown that anti-inflammatory drugs can reduce the incidence of lung cancer. In this scenario, we highlight piperlongumin ...