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Mostrando ítems 11-20 de 1565
Metabolic effects of CoCr-enriched medium on shear-stressed endothelial cell and osteoblasts: A possible mechanism involving a hypoxic condition on bone healing
(2021-09-01)
Cobalt-chromium (CoCr)-based alloys have emerged as an interesting biomaterial within biomedical field, mainly considering their biocompatibility, resistance to corrosion and absence of magnetism; however, its effect on ...
Zoledronic Acid Inhibits Human Osteoblast Activities
(Karger, 2013-01-01)
Background: Bisphosphonates are potent inhibitors of bone resorption. These kinds of drugs, which are used for the treatment of osteolytic diseases, have been associated with the occurrence of oral osteonecrosis, especially ...
Titanium-enriched medium drives low profile of ECM remodeling as a pre-requisite to pre-osteoblast viability and proliferative phenotype
(2018-12-01)
Titanium is widely used for biomedical applications, but little information is being delivered regarding the cellular/molecular mechanisms explaining their efficacy, mainly considering the effects of the Ti-released trace ...
B. Abortus Modulates Osteoblast Function Through the Induction of Autophagy
(Frontiers Media SA, 2018-12)
Osteoarticular brucellosis is the most common localization of human active disease. Osteoblasts are specialized mesenchymal-derived cells involved in bone formation and are considered as professional mineralizing cells. ...
The importance of estrogen for bone protection in experimental hyperthyroidism in human osteoblasts
(2019-08-15)
Triiodothyronine (T3) and estrogen (E2) play important roles in the bone remodeling process and signaling of receptor activator of the nuclear factor-kappa β (RANKL) and osteoprotegerin (OPG) expressed by osteoblasts. ...
Purinergic (ATP) signaling stimulates JNK1 but not JNK2 MAPK in osteoblast-like cells: Contribution of intracellular Ca2+ release, stress activated and L-voltage-dependent calcium influx, PKC and Src kinases
(Elsevier Science Inc, 2008-09-15)
This work shows that ATP activates JNK1, but not JNK2, in rat osteoblasts and ROS-A 17/2.8 osteoblast-like cells. In ROS-A 17/2.8 cells ATP induced JNK1 phosphorylation in a dose- and time-dependent manner. JNK1 phosphorylation ...
The Thyroid Hormone Receptor (TR) beta-Selective Agonist GC-1 Inhibits Proliferation But Induces Differentiation and TR beta mRNA Expression in Mouse and Rat Osteoblast-Like Cells
(SPRINGER, 2009)
Previous studies showed anabolic effects of GC-1, a triiodothyronine (T3) analogue that is selective for both binding and activation functions of thyroid hormone receptor (TR) beta 1 over TR alpha 1, on bone tissue in vivo. ...
Osteoblasts engulf apoptotic bodies during alveolar bone formation in the rat maxilla
(Wiley-Blackwell, 2014)
Aging impairs osteoblast differentiation of mesenchymal stem cells grown on titanium by favoring adipogenesis
(Univ Sao Paulo Fac Odontologia Bauru, 2016-07-01)
Aging negatively affects bone/titanium implant interactions. Our hypothesis is that the unbalance between osteogenesis and adipogenesis induced by aging may be involved in this phenomenon. Objective: We investigated the ...