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Spontaneous mammary carcinomas in female dogs: association between immunohistochemical degrees of neoplasia aggressiveness and residual pyrethroids
(2012)
Of the tumors diagnosed in the female dogs have the highest mammary neoplasias incidence. These neoplasias can be influenced by environmental contaminants. Despite evidence of pyrethroid toxicity, carcinogenic potential ...
MicroRNA and cancer: a focus on mammary tumors in female dogs
(Univ Federal Santa Maria, 2018-01-01)
Mammary tumors are the most frequent tumors reported in female dogs and have great relevance in veterinary oncology; however, little is known about the molecular mechanisms involved in the development of metastasis. An ...
Evaluation of vascular endothelial growth factor gene and protein expression in canine metastatic mammary carcinomas
(Wiley-Blackwell, 2016-11-01)
Vascular endothelial growth factor (VEGF) is a potent angiogenic factor that could be associated with the induction of endothelial cell proliferation and metastasis. In this study, we evaluated VEGF gene and protein ...
Hormonal Carcinogenesis in Canine Mammary Cancer: Molecular Mechanisms of Estradiol Involved in Malignant Progression
(MDPI, 2021)
Canine mammary cancer corresponds to a tumor disease that frequently affects female dogs, especially those that are reproductively intact. This disease can decrease the survival and quality of life of affected animals; ...
A hypothesis to relate salivary tumors with mammary and prostate neoplasias
(Biomedical Informatics Publishing Group, 2005)
Salivary, mammary and prostate glands are sex hormone-dependent organs sharing common aspects in structure, hormonal responsiveness and tumor histopathology. Salivary tumors (especially the malignant types) are not as ...
Canine mammary neoplasms: evaluation of tumor microenvironment
(Universidade Federal do Rio Grande do Sul, 2022)
Immunohistochemical and molecular analysis of caveolin-1 expression in canine mammary tumors
(Funpec-editora, 2012-01-01)
Caveolin-1 (Cav-1) is a structural protein present in invaginations of the cell membrane. In human breast cancer, the cav-1 gene is believed to be a tumor suppressor gene associated with inhibition of tumor metastasis. ...
Prevalência dos tumores mamários em gatas na região central do Rio Grande do Sul
(Universidade Federal de Santa MariaBRMedicina VeterináriaUFSMPrograma de Pós-Graduação em Medicina Veterinária, 2013-02-18)
Cancer is one of the main causes of death in dogs and cats and the mammary neoplasm
is one of the most frequent in these species. Although some studies have been performed,
there is little data on the epidemiology of ...
Human chorionic gonadotropin (hCG) up-regulates wnt5b and wnt7b in the mammary gland, and hCGbeta transgenic female mice present with mammary Gland tumors exhibiting characteristics of the Wnt/beta-catenin pathway activation
(Endocrine Society, 2007-08)
Transgenic (TG) mice expressing human chorionic gonadotropin (hCG) beta-subunit under the ubiquitin C promoter, presenting with a moderately elevated level of LH/hCG bioactivity develop multiple neoplasms secondary to the ...
Deregulation of VEGFR-2 and PDGFR expression and microvascular density in a triple-negative model of canine malignant mammary tumors with lymph node or lung metastasis
(2019-01-01)
Canine mammary tumors (CMT) represent the most common cancer in noncastrated female dogs. Interestingly, triple-negative tumors are the most common molecular subtype in female dogs. In this study, we proposed to evaluate ...