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Parecoxib reduces renal injury in an ischemia/reperfusion model in rats
(Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia, 2015-04-01)
To evaluate the effect of parecoxib (an NSAID) on renal function by measuring plasma NGAL (serum neutrophil gelatinase-associated lipocalin) levels in an induced-ischemia rat model. METHODS: Forty male Wistar rats were ...
Histopathological Effects of Ischemia - Reperfusion on Intestinal Anastomotic Wound Healing in Dogs
(Sociedad Chilena de Anatomía, 2007)
Does propofol and isoflurane protect the kidney against ischemia/reperfusion injury during transient hyperglycemia?
(Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia, 2013-03-01)
PURPOSE: To study the effect of isoflurane (Iso) or propofol (Prop) anesthesia on renal ischemia/reperfusion injury (IRI) during transient hyperglycemia. METHODS: Thirty six rats were randomly assigned into six groups of ...
Ischemic preconditioning and the gene expression of enteric endothelial cell biology of rats submitted to intestinal ischemia and reperfusion
(Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia, 2013-03-01)
PURPOSE: To investigate the effects of ischemic preconditioning (IPC) on the expression of pro and anti-apoptotic genes in rat endothelial cells undergoing enteric ischemia (I) and reperfusion (R). METHODS: Thirty rats ...
TRPM4 activation by chemically- and oxygen deprivation-induced ischemia and reperfusion triggers neuronal death
(Taylor & Francis, 2017)
Cerebral ischemia-reperfusion injury triggers a deleterious process ending in neuronal death. This process has two components, a glutamate-dependent and a glutamate-independent mechanism. In the glutamate-independent ...
Calpain translocation and activation as pharmacological targets during myocardial ischemia/reperfusion
(2010)
Calpains contribute to reperfusion-induced myocardial cell death. However, it remains controversial whether its activation occurs during ischemia or reperfusion. We investigated the regulation and time-course of calpain ...
Cellular mechanisms against ischemia reperfusion injury induced by the use of anesthetic pharmacological agents
(Elsevier, 2014)
Ischemia–reperfusion (IR) cycle in the myocardium is associated with activation of an injurious cascade,
thus leading to new myocardial challenges, which account for up to 50% of infarct size. Some evidence
implicates ...
Molecular mechanisms in liver ischemic-reperfusion injury and ischemic preconditioning Mecanismos moleculares en el daño por isquemia-reperfusión hepática y en el preacondicionamiento isquémico
(2005)
Ischemia-reperfusion (IR) liver injury is associated with temporary clamping of hepatoduodenal ligament during liver surgery, hypoperfusion shock and graft failure after liver transplantation. Mechanisms of IR liver injury ...
The role of ischemic preconditioning and pentoxifylline in intestinal ischemia/reperfusion injury of rats
(Acta Cirurgica Brasileira, 2017)
Purpose: To investigate the role of ischemic preconditioning (IPC) and pentoxifylline (PTX) in intestinal mucosa ischemia/reperfusion injury (IR). Methods: Thirty rats were assigned to 5 groups (N= 6): (CG): no clamping ...