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Mostrando ítems 11-20 de 154
N-Glycosylation of mollusk hemocyanins contributes to their structural stability and immunomodulatory properties in mammals
(2019)
Hemocyanins are widely used as carriers, adjuvants, and nonspecific immunostimulants in cancer because they promote Th1 immunity in mammals. Hemocyanins also interact with glycan-recognizing innate immune receptors on ...
Humoral immune responses of antibacterial hemocyanin (Ab-Hcy) in mud crab, Scylla serrata
(Elsevier B.V., 2016-11-01)
Hemocyanins are large extracellular respiratory proteins distributed within the hemolymph of arthropods, molluscs and larval stages of certain insects. In the present study, we characterized the humoral immune functions ...
TLR4, but Neither Dectin-1 nor Dectin-2, Participates in the Mollusk Hemocyanin-Induced Proinflammatory Effects in Antigen-Presenting Cells From Mammals
(2019)
Mollusk hemocyanins have biomedical uses as carriers/adjuvants and nonspecific immunostimulants with beneficial clinical outcomes by triggering the production of proinflammatory cytokines in antigen-presenting cells (APCs) ...
Concholepas hemocyanin biosynthesis takes place in the hepatopancreas, with hemocytes being involved in its metabolism
(2010)
Hemocyanins are copper-containing glycoproteins in some molluscs and arthropods, and their bestknown function is O2 transport. We studied the site of their biosynthesis in the gastropod Concholepas concholepas by using ...
Characterization of phenoloxidase activity from spider Polybetes pythagoricus hemocyanin
(Wiley-liss, Div John Wiley & Sons Inc, 2015-10)
Hemocyanin of the spider Polybetes pythagoricus, in addition to its typical role as an oxygen transporter, also exhibits a phenoloxidase activity induced by micellar concentrations of SDS. In the present work, we found the ...
Hemocyanin of the caenogastropod Pomacea canaliculata exhibits evolutionary differences among gastropod clades
(Public Library of Science, 2020-01-30)
Structural knowledge of gastropod hemocyanins is scarce. To better understand their evolution and diversity we studied the hemocyanin of a caenogastropod, Pomacea canaliculata (PcH). Through a proteomic and genomic approach, ...