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Monoterpenes affect chlorodiazepoxide–micelle interaction through micellar dipole potential modifications
(Elsevier Science, 2003-10)
The ability of several natural terpenes to affect benzodiazepine (BZD)-micelle interaction through the membrane dipolar organization was investigated. The acid-base equilibrium of chlorodiazepoxide (CDX) and the spectroscopic ...
Effects of a flavonoid-rich fraction on the acquisition and extinction of fear memory: pharmacological and molecular approaches
(Universidade De Fortaleza, 2016)
The effects of flavonoids have been correlated with their ability to modulate the glutamatergic, serotoninergic, and GABAergic neurotransmission: the major targets of these substances are N-methyl-D-aspartic acid receptor ...
Expresion of gamma-aminobutyric acid B receptor subunits in hypothalamus of male and female developing rats
(Elsevier, 2005-12-07)
GABA and its receptors show particular ontogenic distributions in different rat brain areas. Recently, GABAB receptors (GBR) have been described to assemble as heterodimers formed by a GBR1a/b and a GBR2 subunit. Here, the ...
Synthesis and GABAA receptor activity of 2,19-sulfamoyl analogues of allopregnanolone
(Elsevier, 2009)
The synthesis of new analogues of allopregnanolone with a bridged sulfamidate ring over the a−face of ring A has been achieved from easily available precursors, using an intramolecular aziridination strategy. The methodology ...
Maternal exposure to picrotoxin modifies the response of the GABA(A) receptor during sexual behavior of adult male rat offspring
(LIPPINCOTT WILLIAMS & WILKINSPHILADELPHIA, 2012)
This study investigated whether perinatal exposure to picrotoxin, a GABA(A) antagonist, modifies the effect of muscimol, a GABA(A) agonist, on the sexual behavior of adult male rats. Two hours after birth and then once ...
Proenkephalin a and the gamma-aminobutyric acid a receptor pi subunit: expression, localization, and dynamic changes in human secretory endometriumFERTILITY AND STERILITYFERTIL STERIL
(AMERICAN SOCIETY FOR REPRODUCTIVE MEDICINE, 2017)
Dendritic assembly of heteromeric gamma-aminobutyric acid type b receptor subunits in hippocampal neuronsJOURNAL OF BIOLOGICAL CHEMISTRY (PRINT)J BIOL CHEM (PRINT)
(AMERICAN SOCIETY FOR BIOCHEMISTRY AND MOLECULAR BIOLOGY, 2009)
Dendritic assembly of heteromeric gamma-aminobutyric acid type b receptor subunits in hippocampal neuronsJOURNAL OF BIOLOGICAL CHEMISTRY (PRINT)J BIOL CHEM (PRINT)
(AMERICAN SOCIETY FOR BIOCHEMISTRY AND MOLECULAR BIOLOGY, 2009)
Assessment of in vitro pharmacological effect of Neotropical Piperaceae in GABAergic bioassays in relation to plants traditionally used for folk illness by the Yanesha (Peru)
(Elsevier, 2014)
ETHNOPHARMACOLOGICAL RELEVANCE: A previous pilot ethnobotanical and ethnopharmacological study with the Q'echi Maya identified the family Piperaceae, as an important taxonomic group traditionally used for the treatment of ...