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Mostrando ítems 11-20 de 266
Human endogenous RNAs: Implications for the immunomodulation of Toll-like receptor 3
(SPANDIDOS PUBL LTD, 2011)
Toll-like receptors (TLRs), a family of mammalian receptors, are able to recognize nucleic acids. TLR3 recognizes double-stranded (ds)RNA, a product of the replication of certain viruses. Polyinosinic-polycytidylic acid, ...
Simplifying plant gene silencing and genome editing logistics by a one-Agrobacterium system for simultaneous delivery of multipartite virus vectors
(Wiley, 2022-07-14)
Viral vectors provide a quick and effective way to express exogenous sequences in eukaryotic cells and to engineer eukaryotic genomes through the delivery of CRISPR/Cas components. Here, we present JoinTRV, an improved ...
Genome-wide analysis of EgEVE_1, a transcriptionally active endogenous viral element associated to small RNAs in Eucalyptus genomes
(2017-01-01)
Endogenous viral elements (EVEs) are the result of heritable horizontal gene transfer from viruses to hosts. In the last years, several EVE integration events were reported in plants by the exponential availability of ...
Deep sequencing analysis of RNAs from citrus plants grown in a citrus sudden death–affected area reveals diverse known and putative novel viruses
(2017-04-24)
Citrus sudden death (CSD) has caused the death of approximately four million orange trees in a very important citrus region in Brazil. Although its etiology is still not completely clear, symptoms and distribution of ...
Citrus psorosis virus 24K protein interacts with citrus miRNA precursors, affects their processing and subsequent miRNA accumulation and target expression
(2016-04)
Sweet orange (Citrus sinensis), one of the most important fruit crops worldwide, may suffer from disease symptoms induced by
virus infections, thus resulting in dramatic economic losses. Here, we show that the infection ...
Influenza virus RNA polymerase may be activated inside the virion
(Microbiology Society, 2019)
Neutralizing monoclonal antibodies to fight HIV-1 : on the threshold of success
(2017)
Anti-human immunodeficiency virus type-1 (anti-HIV-1) neutralizing monoclonal antibodies are broadening the spectrum of pre- and post-exposure treatment against HIV-1. A better understanding of how these antibodies develop ...
Modulação da expressão de IFITM3 via agonistas dos receptores CCR5 e CXCR4 e sua implicação na replicação dos vírus influenza
(Fiocruz/Instituto de Tecnologia em Imunobiológicos, 2018)
T lymphocytes activated by persistent viral infection differentially modify the expression of metalloproteinases and their endogenous inhibitors, TIMPs, in human astrocytes: Relevance to HTLV-I-induced neurological disease
(American Association of Immunologists, 2000)
Activation of T lymphocytes by human pathogens is a key step in the development of immune-mediated neurologic diseases. Because of their ability to invade the CNS and their increased secretion of proinflammatory cytokines, ...