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Mostrando ítems 11-20 de 188
Adjuvants and delivery systems for antifungal vaccines: Current state and future developments
(Oxford Univ Press, 2015)
Intranasal Delivery of Influenza rNP Adjuvanted with c-di-AMP Induces Strong Humoral and Cellular Immune Responses and Provides Protection against Virus Challenge
(Public Library of Science, 2014-08)
There is a critical need for new influenza vaccines able to protect against constantly emerging divergent virus strains. This will be sustained by the induction of vigorous cellular responses and humoral immunity capable ...
Genetic engineering of Lactococcus lactis co-producing antigen and the mucosal adjuvant 3' 5'- cyclic di Adenosine Monophosphate (c-di-AMP) as a design strategy to develop a mucosal vaccine prototype
(Frontiers Research Foundation, 2018-09)
Lactococcus lactis is a promising candidate for the development of mucosal vaccines. More than 20 years of experimental research supports this immunization approach. In addition, 3' 5'- cyclic di-adenosine monophosphate ...
Oral delivery of Brucella spp. recombinant protein U-Omp16 abrogates the IgE-mediated milk allergy
(Landes Bioscience, 2014-05)
Food allergies are increasingly common disorders and no therapeutic strategies are yet approved. The unlipidated Omp16 (U-Omp16) is the outer membrane protein of 16 kDa from B. abortus and possesses a mucosal adjuvant ...
Stability Studies of the Vaccine Adjuvant U-Omp19
(John Wiley & Sons Inc., 2021-02)
Unlipidated outer membrane protein 19 (U-Omp19) is a novel mucosal adjuvant in preclinical development to be used in vaccine formulations. U-Omp19 holds two main properties, it is capable of inhibiting gastrointestinal and ...
Parenteral adjuvant effects of an enterotoxigenic Escherichia coli natural heat-labile toxin variant
(Frontiers Research FoundationLausanne, 2014-01-07)
Native type I heat-labile toxins (LTs) produced by enterotoxigenic Escherichia coli (ETEC) strains exert strong adjuvant effects on both antibody and T cell responses to soluble and particulate antigens following ...
Progress in the use of antisense oligonucleotides for vaccine improvement
(2020-02-01)
Antisense oligonucleotides (ASOs) are synthetically prepared short single-stranded deoxynucleotide sequences that have been validated as therapeutic agents and as a valuable tool in molecular driving biology. ASOs can block ...
Progress toward a malaria vaccine: Efficient induction of protective anti-malaria immunity
(Walter de Gruyter & Co, 2001-04-01)
Malaria can be a very severe disease, particularly in young children, pregnant women (mostly in primipara), and malaria naive adults, and currently ranks among the most prevalent infections in tropical and subtropical areas ...