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Mostrando ítems 11-20 de 144
Dasatinib Overrides Imatinib Resistance Mediated by the F359I Residue Mutation in Two Patients with Chronic Myeloid Leukemia
(KARGERBASEL, 2012)
Despite the beneficial effects of imatinib mesylate, some patients may either not respond or respond suboptimally. Here, we report two chronic myelogenous leukemia patients; one had a suboptimal response according to ...
Nilotinib is associated with a reduced incidence of BCR-ABL mutations vs imatinib in patients with newly diagnosed chronic myeloid leukemia in chronic phase
(Amer Soc HematologyWashingtonEUA, 2013)
BCR-ABL binds to IRS-1 and IRS-1 phosphorylation is inhibited by imatinib in K562 cells
(Elsevier Science BvAmsterdamHolanda, 2003)
Importance of monitoring and early switch to second generation tyrosine kinase inhibitors for the prognosis of patients with chronic myeloid leukemia with imatinib resistance or intolerance
(Associação Brasileira de Hematologia e Hemoterapia e daSociedade Brasileira de Transplante de Medula Óssea, 2011)
Imatinib mesylate was the first BCR-ABL-target agent approved for the treatment of chronic myeloid leukemia. Although most patients respond well to imatinib therapy, the literature shows that one third develops resistance ...
Importance of monitoring and early switch to second generation tyrosine kinase inhibitors for the prognosis of patients with chronic myeloid leukemia with imatinib resistance or intolerance
(Associação Brasileira de Hematologia e Hemoterapia e daSociedade Brasileira de Transplante de Medula ÓsseaBrasil, 2011)
Dasatinib induces significant hematologic and cytogenetic responses in patients with imatinib-resistant or -intolerant chronic myeloid leukemia in accelerated phase
(Amer Soc HematologyWashingtonEUA, 2007)
Leucemia mielóide crônica: uma revisão de literatura
(Universidade Federal do Rio Grande do NorteBrasilUFRNBiomedicina, 2017-12-04)
This work aimed to perform a bibliographic survey on chronic myeloid leukemia (CML) in scientifc databases in order to obtain a better knowledge about this disease. CML is a myeloproliferative disease, a type of non-hereditary ...