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MIF-driven activation of macrophages induces killing of intracellular Trypanosoma cruzi dependent on endogenous production of tumor necrosis factor, nitric oxide and reactive oxygen species
(Elsevier Gmbh, 2017-02)
The proinflammatory cytokine macrophage migration inhibitory factor (MIF) is a key player in innate immunity. MIF has been considered critical for controlling acute infection by the protozoan Trypanosoma cruzi, but the ...
Bone resorptive activity of osteoclast-like cells generated in vitro by PEG-induced macrophage fusion
(Sociedad de Biología de Chile, 2010)
Effect of Qualea multiflora on Macrophages and Tumour Cells
(Colegio Farmaceuticos Provincia de Buenos Aires, 2013-01-01)
Species of the genus Qualea are used by the Brazilian people as a natural anti-inflammatory. Based on this evidence, we evaluated the effects of terpene fractions beta F and TF (rich in beta-sitosterol and terpenoids, ...
Effect of Qualea multiflora on macrophages and tumour cells
(2013-12-23)
Species of the genus Qualea are used by the Brazilian people as a natural anti-inflammatory. Based on this evidence, we evaluated the effects of terpene fractions βF and TF (rich in β-sitosterol and terpenoids, respectively) ...
Protective role of ACE2 and its downregulation in SARS-CoV-2 infection leading to macrophage activation syndrome: Therapeutic implications
In light of the outbreak of the 2019 novel coronavirus disease (COVID-19), the international scientific community has joined forces to develop effective treatment strategies. The Angiotensin-Converting Enzyme (ACE) 2,
is ...
Biological and inflammatory effects of antigen 5 from polybia paulista (Hymenoptera, vespidae) venom in mouse intraperitoneal macrophages
(2021-12-01)
The social wasp Polybia paulista (Hymenoptera, Vespidae) is highly aggressive, being responsible for many medical occurrences. One of the most allergenic components of this venom is Antigen 5 (Poly p 5). The possible ...
Macrophage polarization: implications on metabolic diseases and the role of exercise
(Consel Brasil Oftalmologia, 2016)
Macrophages are cells of the innate immune response that trigger inflammation resolution. The phenotype of "classically activated macrophages" (M1) has anti-tumoricidal and anti-bactericidal activities. On the other hand, ...
Diphenyl diselenide-modulation of macrophage activation: Down-regulation of classical and alternative activation markers
(Sage Publications Ltd, 2012-01)
Diphenyl diselenide ((PhSe)2), a simple organoselenium compound, possesses interesting pharmacological properties that are under extensive research. As macrophages respond to microenvironmental stimuli and can display ...