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Zebrafish Models of Kidney Damage and Repair
(Springer, 2015-06)
The vertebrate kidney possesses the capacity to repair damaged nephrons, and this potential is conserved regardless of the complexity of species-specific kidneys. However, many aquatic vertebrates possess the ability to ...
Estudo sobre o papel da dopamina no desenvolvimento e no comportamento tipo-ansioso em larvas de Zebrafish (Danio rerio) utilizando teste de Labirinto em cruz com rampa adaptado para larvas
(Universidade Federal de Minas GeraisBrasilICB - INSTITUTO DE CIÊNCIAS BIOLOGICASPrograma de Pós-Graduação em NeurociênciasUFMG, 2020-10-22)
The use of model animals in behavioral research is increasing. The use of these animals has become more diverse over the years compared to the beginning when only rodents or primates were used for research. Due to the ...
In vivo Host-Pathogen interaction as revealed by global proteomic profiling of zebrafish larvae
(Frontiers media SA, 2017)
The outcome of a host-pathogen interaction is determined by the conditions of the host, the pathogen, and the environment. Although numerous proteomic studies of in vitro-grown microbial pathogens have been performed, in ...
Insights from zebrafish and mouse models on the activity and safety of ar-turmerone as a potential drug candidate for the treatment of epilepsy
(2013)
In a previous study, we uncovered the anticonvulsant properties of turmeric oil and its sesquiterpenoids (ar- turmerone, α-, β-turmerone and α-atlantone) in both zebrafish and mouse models of chemically-induced seizures ...
In vivo study of teratogenic and anticonvulsant effects of antiepileptics drugs in zebrafish embryo and larvae
(Pergamon-Elsevier Science Ltd, 2018-03)
Epilepsy is a neurological disorder treated with antiepileptic drugs (AEDs). Since AEDs are administered in women in childbearing age, it is critical to study if drugs are capable of inducing developmental toxicity. Along ...
Nutraceutical emulsion containing valproic acid (NE-VPA): a drug delivery system for reversion of seizures in zebrafish larvae epilepsy model
(Springer Netherlands, 2017-09)
Valproic acid (VPA) is an antiepileptic drug, which is currently used in neurodegenerative diseases. However, a high dose is required to obtain a therapeutic effect. Long-chain polyunsaturated fatty acids (PUFAs), such as ...
Folic acid magnetic nanotheranostics for delivering doxorubicin: Toxicological and biocompatibility studies on Zebrafish embryo and larvae
(Academic Press Inc Elsevier Science, 2018-11)
Doxorubicin (DOXO) is a chemotherapeutic agent widely used for the treatment of solid tumors and hematologic malignancies in both adults and children. However, DOXO causes short- and long-term cardiotoxicity and others ...
Utilização de zebrafish para validação de programa computacional aplicado à análise cardíaca após administração de medicamentos cardiotônicos
(Universidade Federal de São CarlosUFSCarPrograma de Pós-Graduação em Conservação da Fauna - PPGCFauCâmpus São Carlos, 2020-06-15)
The zebrafish (Danio rerio) is a vertebrate widely used as a model for laboratory tests,
due to its high fertility, practical handling and low cost. The cardiac characteristics of this
species, as well, as the easy ...