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Mostrando ítems 11-20 de 101
Quasispecies of hepatitis C virus genotype 1 and treatment outcome with Peginterferon and Ribavirin
(Elsevier B.V., 2009-07-01)
The majority of patients with chronic hepatitis C fail to respond to antiviral therapy. The genetic basis of this resistance is unknown. The quasispecies nature of HCV may have an important implication concerning viral ...
Análise das quasiespécies do vírus da hepatite C genótipo 1 por meio da região genômica NS5A
(Universidade Estadual Paulista (Unesp), 2011-02-25)
A composição de quasiespécies do vírus da Hepatite C (HCV) pode ter implicações importantes com relação à persistência viral e à resposta a terapia baseada em Interferon. A região NS5A completa foi analisada para avaliar ...
Hepatitis C virus quasispecies in plasma and peripheral blood mononuclear cells of treatment naive chronically infected patients
(WILEY, 2009)
Peripheral blood mononuclear cells (PBMCs) from 45 treatment naive, HIV-negative, chronically hepatitis C virus (HCV)-infected patients were analyzed for the presence of HCV RNA. Viral RNA was detected in 73% of the studied ...
Análise das quasiespécies do vírus da hepatite C genótipo 1 por meio da região genômica NS5A
(Universidade Estadual Paulista (UNESP), 2014)
A beginner’s guide for FMDV quasispecies analysis: sub-consensus variant detection and haplotype reconstruction using next-generation sequencing
(Oxford Academic Press, 2020-09)
Deep sequencing of viral genomes is a powerful tool to study RNA virus complexity. However, the analysis of next-generation sequencing data might be challenging for researchers who have never approached the study of viral ...
Comparative analysis of hepatitis B virus genotype a molecular evolution in patients infected with HBV and in patients co-infected with HBV and HIV
(Wiley-liss, div John Wiley & Sons Inc., 2012-04)
HIV infection has a significant impact on the natural progression of liver disease caused by infection with hepatitis B virus (HBV), but its role in the molecular evolution of HBV is unknown. It is difficult to study the ...