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Historic of therapeutic efficacy of albendazol sulphoxide administered in different routes, dosages and treatment schemes, against Taenia saginata in cattle experimentally infected
(Elsevier B.V., 2014-02-01)
The present study aimed to notify the history of albendazole sulphoxide (ALB-SO) and albendazole (ALBZ) efficacy against Taenia saginata cysticercus (Cysticercus bovis) parasitizing experimentally infected bovines. A total ...
Tafenoquine treatment of Plasmodium vivax malaria: suggestive evidence that CYP2D6 reduced metabolism is not associated with relapse in the Phase 2b DETECTIVE trial
(BioMed Central, 2016)
Background: Tafenoquine (TQ) and primaquine (PQ) are 8-aminoquinolines (8-AQ) with anti-hypnozoite activity against vivax malaria. PQ is the only FDA-approved medicine for preventing relapsing Plasmodium vivax infection ...
Evaluation of the efficacy and security of quinfamide administered in a single dose of 300 mg in adult patients with intestinal amebiasis
(Sociedad Chilena de Parasitología, 2005)
Pharmacological perspective: glycyrrhizin may be an efficacious therapeutic agent for COVID-19
Coronavirus disease 2019 (COVID-19) caused by the previously unknown pathogen, severe acute respiratory syndrome-related coronavirus-2 (SARS-CoV-2) is now a global pandemic. There are no vaccines or
specific treatments ...
From ligand design to therapeutic efficacy: the challenge for nicotinic receptor research
(ELSEVIER SCI LTD, 2005-12)
S-Nicotine, the principal psychoactive constituent of Nicotiana tabacum, underpins addiction to tobacco smoking. Although tobacco consumption is a leading cause of death worldwide, nicotine itself is also proposed to have ...
Development of Quantitative Real-Time PCR (TaqMan Triplex System) for the Diagnosis and Evaluation of Therapeutic Efficacy in Chagas Disease
(Fiocruz/Instituto de Tecnologia em Imunobiológicos, 2019)
Field trial assessment of ivermectin pharmacokinetics and efficacy against susceptible and resistant nematode populations in cattle
(Elsevier Science, 2018-05)
The study compared the pharmacokinetic (PK) behaviour and anthelmintic efficacy against susceptible and resistant nematodes following subcutaneous (SC) and oral administration of ivermectin (IVM) to cattle. Six commercial ...
Therapeutic efficacy of albendazole against soil-transmitted helminthiasis in children measured by five diagnostic methods
(Public Library of Science, 2023)
Pharmacokinetic profile and anthelmintic efficacy of moxidectin administered by different doses and routes to feedlot calves
(Elsevier Science, 2019-02)
We evaluated the comparative plasma disposition kinetics and efficacy of moxidectin (MXD), administered by the intraruminal (IR) or subcutaneous (SC) route at two different dosage levels (0.2 and 1 mg/kg) in feedlot calves. ...
A systematic review and meta-analysis of adjunctive therapies in diabetic foot ulcers
(Elsevier, 2016)
BACKGROUND: Multiple adjunctive therapies have been proposed to accelerate wound healing in patients with diabetes and foot ulcers. The aim of this systematic review is to summarize the best available evidence supporting ...