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46,XY DSD due to impaired androgen production
(ELSEVIER SCI LTD, 2010)
Disorders of androgen production can occur in all steps of testosterone biosynthesis and secretion carried out by the foetal Leydig cells as well as in the conversion of testosterone into dihydrotestosterone (DHT). The ...
DSD Due to 5 alpha-Reductase 2 Deficiency - from Diagnosis to Long Term Outcome
(THIEME MEDICAL PUBL INCNEW YORK, 2012)
Most of the patients with 5 alpha-RD 2 deficiency are reared in the female social sex due to their severely undervirilized external genitalia but similar to 60% who have not been submitted to orchiectomy in childhood undergo ...
Evaluation of the tubular and interstitial functions of the testis in 46,XY patients with ambiguous genitalia
(Freund Publishing House LtdLondonInglaterra, 2000)
Inhibition of 5-alpha-reductase activity induces stromal remodeling and smooth muscle de-differentiation in adult gerbil ventral prostate
(Blackwell Verlag Gmbh, 2004-06-01)
Prostatic differentiation during embryogenesis and its further homeostatic state maintenance during adult life depend on androgens. Dihydrotestosterone, which is synthesized from testosterone by 5alpha-reductase (5alpha-r), ...
Inhibition of 5-alpha-reductase activity induces stromal remodeling and smooth muscle de-differentiation in adult gerbil ventral prostate
(Blackwell Verlag Gmbh, 2004-06-01)
Prostatic differentiation during embryogenesis and its further homeostatic state maintenance during adult life depend on androgens. Dihydrotestosterone, which is synthesized from testosterone by 5alpha-reductase (5alpha-r), ...
Increased Androgen Receptor and Remodeling in the Prostatic Stroma After the Inhibition of 5-Alpha Reductase and Aromatase in Gerbil Ventral Prostate
(Wiley-liss, 2009-12-01)
Prostate require high levels of steroidogenic enzymes such as 5 alpha-reductase (5 alpha-r) and Aromatase (Aro) for the formation of active steroids. Dihydrotestosterone (DHT), the prostate dominant androgen, is converted ...