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Cell cycle, telomeres, and telomerase in leishmania spp.: What do we know so far?
(2021-11-01)
Leishmaniases belong to the inglorious group of neglected tropical diseases, presenting different degrees of manifestations severity. It is caused by the transmission of more than 20 species of parasites of the Leishmania ...
Expressões da proteína survivina e da enzima telomerase em colo uterino de mulheres portadoras ou não de lesões induzidas pelo papilomavírus humano
(Universidade Federal de São Paulo (UNIFESP), 2010)
Telomerase as a cancer target. Development of new molecules
(Cell Press, 2002-10)
Telomeres are the terminal part of the chromosome containing a long repetitive and non-codifying sequence that has as function protecting the chromosomes. In normal cells, telomeres lost part of such repetitive sequence ...
Telomere and Telomerase Biology
(Elsevier B.V., 2014-01-01)
Telomeres are the physical ends of eukaryotic linear chromosomes. Telomeres form special structures that cap chromosome ends to prevent degradation by nucleolytic attack and to distinguish chromosome termini from DNA ...
Atividade da telomerase e proliferação de células de melanoma HS839.T submetidas ao AZT
(Universidade Federal de São Paulo (UNIFESP), 2009)
Introdução: O melanoma é decorrente de um crescimento celular descontrolado, com perda de inibição por contato e alterações no núcleo, afetando a manutenção dos telômeros. A telomerase, responsável pela síntese do telômero, ...
Increased fibroblast telomerase expression precedes myofibroblast alpha-smooth muscle actin expression in idiopathic pulmonary fibrosis
(HOSPITAL CLINICAS, UNIV SAO PAULOSAO PAULO, 2012)
OBJECTIVE: This study sought to identify the relationship between fibroblast telomerase expression, myofibroblasts, and telomerase-mediated regulatory signals in idiopathic pulmonary fibrosis. METHODS: Thirty-four surgical ...
Increased fibroblast telomerase expression precedes myofibroblast α-smooth muscle actin expression in idiopathic pulmonary fibrosis
(Faculdade de Medicina / USP, 2012)
OBJECTIVE: This study sought to identify the relationship between fibroblast telomerase expression, myofibroblasts, and telomerase-mediated regulatory signals in idiopathic pulmonary fibrosis. METHODS: Thirty-four surgical ...