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Vitamin A Impairs the Reprogramming of Tregs into IL-17-Producing Cells during Intestinal Inflammation
(Hindawi Publishing, 2015)
Maintaining the identity of Foxp3+ regulatory T cells (Tregs) is critical for controlling immune responses in the gut, where an
imbalance between Tregs and T effector cells has been linked to inflammatory bowel disease. ...
Neuropilin-1 is not a marker of human Foxp3+ Treg
(Wiley, 2018)
Imbalanced expression of functional surface molecules in regulatory and effector T cells in systemic lupus erythematosus
(Associação Brasileira de Divulgação Científica, 2014-08-01)
Regulatory T (TREG) cells play an important role in maintaining immune tolerance and avoiding autoimmunity. We analyzed the expression of membrane molecules in TREG and effector T cells in systemic lupus erythematosus ...
Sporothrix brasiliensis induces a more severe disease associated with sustained Th17 and regulatory T cells responses than Sporothrix schenckii sensu stricto in mice
(2018-01-01)
Little is known about the differences in the CD4+ T-cell response induced by Sporothrix schenckii and Sporothrix brasiliensis, the most virulent species that cause sporotrichosis. Here, the helper (Th) and regulatory T ...
Pregnancy-specific glycoprotein 1a activates dendritic cells to provide signals for Th17-, Th2-, and Treg-cell polarization
(Wiley VCH Verlag, 2012-06)
Because of their plasticity and central role in orchestrating immunity and tolerance, DCs can respond to pregnancy-specific signals, thus promoting the appropriate immune response in order to support pregnancy. Here, we ...
Role of the phenotypic and functional stability of regulatory T lymphocytes in the alveolar bone resorption during experimental periodontitis
(2020)
Periodontitis is a chronic inflammatory disease associated with the formation of dysbiotic plaque biofilms and characterized by the progressive destruction of the tooth‐supporting apparatus (periodontium). The alveolar ...
Mecanismos de supresión de las células T reguladoras (Treg)
(Gaceta Médica de México. 2013;149 630, 2015)
A physiological role for inducible FOXP3+ TREG cells: Lessons from women with reproductive failure
(Elsevier Inc, 2010-09)
We have previously shown a decreased frequency and function of Tregs in women suffering from recurrent spontaneous abortions (RSA). In the current study, we first investigated the expression of FOXP3 after T-cell activation. ...