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Mostrando ítems 11-20 de 119
Enriquecimiento de mutaciones en el cáncer de mama triple negativo metastásico
(PE, 2022)
Antecedentes: El Cáncer de Mama Triple Negativo (TNBC) es una enfermedad heterogénea con
biología agresiva y evolución tumoral compleja. El propósito fue identificar el enriquecimiento de
las alteraciones genómicas del ...
Primary relapse site pattern in women with triple-negative breast cancer
(Elsevier B.V., 2014-01-01)
Despite the remarkable improvements in breast cancer (BC) characterization, accurate prediction of BC clinical behavior is often still difficult to achieve. Some studies have investigated the association between the molecular ...
Therapeutic opportunities for PLK1 inhibitors: Spotlight on BRCA1-deficiency and triple negative breast cancers
(Elsevier Science, 2020-05)
Polo-Like Kinases (PLKs) are central players of mitotic progression in Eukaryotes. Given the intimate relationship between cell cycle progression and cancer development, PLKs in general and PLK1 in particular have been ...
Antitumoral and antimetastatic activity of Maitake D-Fraction in triple-negative breast cancer cells
(Impact Journals, 2018-05-04)
Triple-negative breast cancer (TNBC) is associated with poor prognosis, high local recurrence rate and high rate of metastasis compared with other breast cancer subtypes. In addition, TNBC lacks a targeted therapy. This ...
Tratamiento selectivo de cáncer de seno triple negativo, afectando la bioenergética mitocondrial [recurso electrónico]
(2019-10-09)
El cáncer de seno triple negativo (TNBC), es la forma más agresiva de cáncer de seno, caracterizada por no expresar receptores de estrógenos (ER), receptores de progesterona (PR) y receptor 2 del factor de crecimiento ...
Preclinica studies of the combination of EM1 calcitrol analogue with paclitaxel in TNBC
(Fundacion Revista Medicina, 2018)
Triple negative breast cancer (TNBC) does not respond to current targeted therapies as it lacks the expression of hormone receptors and epidermal growth factor receptor HER2. Therefore, current treatment options include ...
Identification of cleavage regulatory mechanisms and phenotypic consequences to targeting of the ADAM 17/ EGFR axis in triple negative breast cancer (TNBC) in-vitro
(Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica, 2015)
Obesidad como riesgo para el desarrollo de cáncer de mama triplenegativo en pacientes hospital III-1 ESSALUD José Cayetano Heredia, Piura 2015- 2019
(Universidad Privada Antenor OrregoPE, 2024)
Introducción: El Cáncer de Mama Triple-Negativo (CMTN), se caracteriza por la
ausencia de receptores hormonales, a diferencia del resto de subtipos (CMRH). Es uno
de los subtipos de cáncer de mama más agresivos, de ...
Role of Hedgehog Signaling in Breast Cancer: Pathogenesis and Therapeutics
(MDPI, 2019-04)
Breast cancer (BC) is the leading cause of cancer-related mortality in women, only followed by lung cancer. Given the importance of BC in public health, it is essential to identify biomarkers to predict prognosis, predetermine ...