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Cytokine and autoantibody clusters interaction in systemic lupus erythematosus
Background: Evidence supports the existence of different subphenotypes in systemic lupus erythematosus (SLE) and the pivotal role of cytokines and autoantibodies, which interact in a highly complex network. Thus, understanding ...
Acidente Vascular Cerebral na Hemoglobinopatia SC (HBB glu6val e glu6lys): avaliação de marcadores de prognóstico
(Centro de Pesquisas Gonçalo Moniz, 2017)
PTPN22 Association in Systemic Lupus Erythematosus (SLE) with Respect to Individual Ancestry and Clinical Sub-Phenotypes
(Universidad del Rosario, 2013)
Protein tyrosine phosphatase non-receptor type 22 (PTPN22) is a negative regulator of T-cell activation associated with several autoimmune diseases, including systemic lupus erythematosus (SLE). Missense rs2476601 is ...
Ldh And Age Are Associated With Hemolysis-endothelial Dysfunction In Hbsc Patients
(Academic Press Inc Elsevier ScienceSan Diego, 2016)
Ldh And Age Are Associated With Hemolysis-endothelial Dysfunction In Hbsc Patients
(ACADEMIC PRESS INC ELSEVIER SCIENCESAN DIEGO, 2016)
Common mechanisms of autoimmune diseases (the autoimmune tautology)
The fact that autoimmune diseases share subphenotypes, physiopathological mechanisms and genetic factors has been called autoimmune tautology, and indicates that they have a common origin. The autoimmune phenotypes vary ...
The diagnosis and clinical significance of polyautoimmunity
Autoimmune diseases (ADs) are chronic and heterogeneous conditions that affect specific target organs or multiple organ systems. The chronic nature of these diseases places a significant burden on the utilization of medical ...
The autoimmune tautology: From polyautoimmunity and familial autoimmunity to the autoimmune genes.
Autoimmune diseases (ADs) are chronic conditions initiated by the loss of immunological tolerance to self-antigens and represent a heterogeneous group of disorders that afflict specific target organs or multiple organ ...
The autoimmune tautology with a focus on antiphospholipid syndrome
Autoimmune diseases (ADs) are often diagnosed according to classification criteria; however, they share similar subphenotypes including signs and symptoms, non-specific autoantibodies and other immune changes, which are ...
SAT0319 Severity in systemic lupus erythematosus patients: A latent trait analysis
Background Systemic Lupus Erythematosus (SLE) is a complex disease which can potentially involve any organ and, therefore, has a wide range of clinical manifestations (i.e., subphenotypes)