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Central inhibition of nitric oxide synthesis blocks the cardiovascular responses induced by moxonidine in anesthetized rats
(Federation Amer Soc Exp Biol, 2004-03-24)
Synthesis of the Macrolactone of Migrastatin and Analogues with Potent Cell-Migration Inhibitory Activity
(WILEY-BLACKWELL, 2010)
The synthesis of the macrolactone core of migrastatin 2, its potent anti-metastasis analogue 34, and ester derivatives 35 and 38 are reported. The approach involves the use of a dihydroxylation reaction to establish the ...
Synthesis of the macrolactone of migrastatin and analogues with potent cell-migration inhibitory activity
(Wiley-VCH VerlagWeinheim, 2010-12)
The synthesis of the macrolactone core of migrastatin 2, its potent anti-metastasis analogue 34, and ester derivatives 35 and 38 are reported. The approach involves the use of a dihydroxylation reaction to establish the ...
Design and Synthesis of 2-Acetamido-2,3-dideoxythiodisaccharides via Diastereoselective Conjugate Addition to Sugar Enone O-Acetyl Oximes. Galactosidase Inhibition Studies
(American Chemical Society, 2018-10)
The key step in a new synthesis of 2-acetamido-2,3-dideoxy-(14)-thiodisaccharides was the conjugate addition of a 1-thiogalactose derivative to E and Z acetyl oximes derived from sugar enones. This reaction was shown to ...
Amphibian oocyte maturation and protein synthesis: related inhibition by cyclic AMP, theophylline, and papaverine
(1978)
Two inhibitors of cyclic AMP phosphodiesterase (3':5'-cyclic-AMP 5'-nucleotidohydrolase, EC 3.1.4.17), theophylline and papaverine, inhibit the maturation of Xenopus laevis oocytes induced by 4 different stimuli: human ...
Inhibition of heparin synthesis by methotrexate in rats in vivo
(Elsevier B.V., 2002-07-15)
The content and synthesis of heparin and mast cell-dependent skin oedema (as an indirect evaluation of histamine and serotonin content) were investigated in the rat skin after chronic treatment with compound 48/80, a mast ...
Inhibition of Junin virus RNA synthesis by an antiviral acridone derivative
(Elsevier Science, 2012-01)
There are no specific approved drugs for the treatment of agents of viral hemorrhagic fevers (HF) and antiviral therapies against these viruses are urgently needed. The present study characterizes the potent and selective ...