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Assessment of tolerance to the effects of methamphetamine on daytime and nighttime activity evaluated with actigraphy in rhesus monkeys
(Springer, 2017)
Methamphetamine is one of the most largely consumed illicit drugs, and its use is associated with abuse liability and several adverse health effects, such as sleep impairment. Importantly, sleep quality can influence ...
Self-cleaning in public procurement (general considerations)Self-cleaning en la contratación pública (consideraciones generales)
(Revista de Derecho Administrativo, 2019)
Intranasal mesenchymal stem cell secretome administration markedly inhibits alcohol and nicotine self-administration and blocks relapse-intake: mechanism and translational options
(2019)
Background: Chronic consumption of most drugs of abuse leads to brain oxidative stress and neuroinflammation, which inhibit the glutamate transporter GLT-1, proposed to perpetuate drug intake. The present study aimed at ...
Prenatal exposure to ethanol during late gestation facilitates operant self-administration of the drug in 5-day-old rats
(Elsevier Science Inc, 2014-02)
Prenatal ethanol exposure modifies postnatal affinity to the drug, increasing the probability of ethanol use and abuse. The present study tested developing rats (5-day-old) in a novel operant technique to assess the degree ...
Stress induces behavioral sensitization, increases nicotine-seeking behavior and leads to a decrease of CREB in the nucleus accumbens
(Pergamon-Elsevier B.V. Ltd, 2012-05-01)
Experimental evidence shows that exposure to stress engenders behavioral sensitization and increases drug-seeking and leads to intense drug taking. However the molecular mechanisms involved in these processes is not well ...
Relationship between ethanol and sucrose self-administration and schedule-induced polydipsia
(PERGAMON-ELSEVIER SCIENCE LTD, 2008)
Studies have suggested a relationship between drug abuse and compulsive behaviors. The present experiments investigated the relationship between schedule-induced polydipsia (SIP) and self-administration (SA) of ethanol and ...
Open-label, multicenter study of self-administered icatibant for attacks of hereditary angioedema
(Wiley Blackwell Publishing, Inc, 2014-03)
Background: Historically, treatment for hereditary angioedema (HAE) attacks has been administered by healthcare professionals (HCPs). Patient self-administration could reduce delays between symptom onset and treatment, and ...
Systemic and intra-accumbal administration of the 5-ht1b receptor agonist CP94253 modulates oral self-administration of ethanol in ratsLa administración sistémica e intra-accumbens del agonista 5-HT1B CP94253 modula la auto-administración oral de etanol en ratas
(Universidad Nacional de Córdoba, 2022)