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Nanoscale sub-compartmentalization of the dendritic spine compartment
(MDPI, 2021)
Abstract: Compartmentalization of the membrane is essential for cells to perform highly specific tasks
and spatially constrained biochemical functions in topographically defined areas. These membrane
lateral heterogeneities ...
Transmisión sináptica-canales de calcio y liberación de neurotransmisore
(Universidad del RosarioEscuela de Medicina y Ciencias de la Salud, 2010)
Neuronal communication in the nervous system is mediated, in the vast majority of animals, by chemical synaptic transmission. In most cases this junctional communication occurs via the release of a transmitter substance, ...
A deep learning-based approach to model anomalous diffusion of membrane proteins: the case of the nicotinic acetylcholine receptor
(Oxford University Press, 2022)
Abstract:
We present a concatenated deep-learning multiple neural network system for the analysis of single-molecule trajectories. We apply this machine learning-based analysis to characterize the translational diffusion ...
Cholesterol modulates acetylcholine receptor diffusion by tuning confinement sojourns and nanocluster stability
(Nature Research, 2018)
Abstract: Translational motion of neurotransmitter receptors is key for determining receptor number at the synapse and hence, synaptic efficacy. We combine live-cell STORM superresolution microscopy of nicotinic acetylcholine ...
Caracterización de la proteína Marlin-2
(Universidad de Chile, 2006)
En el sistema nervioso, la transmisión del impulso nervioso entre neuronas se efectúa a través de la sinapsis. Éstas pueden ser de dos tipo, eléctricas y químicas. En estas últimas existen diversas proteínas que se asocian ...
Application of artificial intelligence strategies to the analysis of neurotransmitter receptor dynamics in living cells
(Cambridge University Press, 2020)
Abstract: Storm (stochastical optical reconstruction microscopy), a form of single-molecule nanoscopy,
calls for a variety of statistical and mathematical operations to reconstruct the original objects from
their noisy ...