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Characterization of the mechanisms underlying the crosstalk between galectins and notch in gastric cancer
(London, 2013)
Gastric cancer is the fourth most common cancer and the second leading cause of cancer-related deaths worldwide. Galectins form a family of β-galactosides binding proteins that recognize a variety of glycan-containing ...
Dampening the signals transduced through hedgehog via microRNA miR-7 facilitates Notch-induced tumourigenesis
(Public Library Science, 2013-05-07)
Fine-tuned Notch and Hedgehog signaling pathways via attenuators and dampers have long been recognized as important<br />mechanisms to ensure the proper size and differentiation of many organs and tissues. This notion is ...
Association of Notch-1, osteopontin and stem-like cells in ENUglioma malignant process
(Impact Journals LLC, 2018)
A link between Notch and progesterone maintains the functionality of the rat corpus luteum
(Bioscientifica, 2015-01)
In this study, we investigated the interaction between the Notch pathway and progesterone to maintain the functionality of the corpus luteum(CL).WhenNotch signaling is activated, the g-secretase complex releases the active ...
Notch system is differentially expressed and activated in pituitary adenomas of distinct histotype, tumor cell lines and normal pituitaries
(Impact Journals LLC, 2017-07)
Pituitary adenomas are among the most frequent intracranial neoplasms andtreatment depends on tumor subtype and clinical features. Unfortunately, nonresponder cases occur, then new molecular targets are needed.Notch system ...
Phosphatidic acid increases Notch signalling by affecting Sanpodo trafficking during Drosophila sensory organ development
(Nature, 2020)
Organ cell diversity depends on binary cell-fate decisions mediated by the Notch signalling pathway
during development and tissue homeostasis. A clear example is the series of binary cell-fate decisions
that take place ...
Expresión de Hey1 al realizar la pérdida de función de NotchIC en las prominencias maxilar y mandibular de embriones de pollo.
(2019)
La vía de señalización Notch es compleja puesto que es temporal y contexto- dependiente; durante la diferenciación celular está involucrada repetidamente en gran variedad de procesos y su modulación tiene un potencial ...
Neurotrophins acting via trkb receptors activate thejagged1-notch2 cell-cell communication pathway tofacilitate early ovarian development
(ASSOCIATION FOR THE STUDY OF INTERNAL SECRETIONS, 2011)
Neurotrophins acting via TRKB receptors activate the JAGGED1-NOTCH2 cell-cell communication pathway to facilitate early ovarian development
(2011)
Tropomyosin-related kinase (TRK) receptor B (TRKB) mediates the supportive actions of neurotrophin 4/5 and brain-derived neurotrophic factor on early ovarian follicle development. Absence of TRKB receptors reduces granulosa ...