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Long-Range RNA-RNA Interactions Circularize the Dengue Virus Genome
(American Society for Microbiology, 2005-05)
Secondary and tertiary RNA structures present in viral RNA genomes play essential regulatory roles during translation, RNA replication, and assembly of new viral particles. In the case of flaviviruses, RNA-RNA interactions ...
Differential RNA sequence requirement for dengue virus replication in mosquito and mammalian cells
(American Society for Microbiology, 2013-08)
Dengue virus cycles between mosquitoes and humans. Each host provides a different environment for viral replication, imposing different selective pressures. We identified a sequence in the dengue virus genome that is ...
Dynamic RNA structures in the dengue virus genome
(Landes Bioscience, 2011)
Dengue virus is an important human pathogen that belongs to the Flaviviridae family. The viral genome is a single molecule of RNA of positive polarity that plays multiple roles during the viral life cycle. Besides encoding ...
Deciphering the RNA landscape by RNAome sequencing
Current RNA expression profiling methods rely on enrichment steps for specific RNA classes, thereby not detecting all RNA species in an unperturbed manner. We report strand-specific RNAome sequencing that determines ...
Identifying trypanosome protein-RNA interactions using RIP-Seq
(Humana Press, 2020)
Trypanosomatids rely primarily on post-transcriptional mechanisms for the control of gene expression, with regulation of RNA processing, localization, degradation and translation by RNA-binding proteins (RBPs). To determine ...
Reverse Transcription Errors and RNA-DNA Differences at Short Tandem Repeats
(2016-07-12)
Transcript variation has important implications for organismal function in health and disease. Most transcriptome studies focus on assessing variation in gene expression levels and isoform representation. Variation at the ...
Reverse Transcription Errors and RNA-DNA Differences at Short Tandem Repeats
(2016-07-12)
Transcript variation has important implications for organismal function in health and disease. Most transcriptome studies focus on assessing variation in gene expression levels and isoform representation. Variation at the ...