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Quantification of Treg cells in peripheral blood and lymph nodes of dogs with multicentric lymphoma
(2017-11-01)
Lymphoma is a malignant tumor characterized by cell proliferation of lymphoid origin and corresponds to 90% of all hematopoietic neoplasms of dogs. Regulatory T cells (Tregs) have been the target of many investigations in ...
Vitamin A Impairs the Reprogramming of Tregs into IL-17-Producing Cells during Intestinal Inflammation
(Hindawi Publishing, 2015)
Maintaining the identity of Foxp3+ regulatory T cells (Tregs) is critical for controlling immune responses in the gut, where an
imbalance between Tregs and T effector cells has been linked to inflammatory bowel disease. ...
Sporothrix brasiliensis induces a more severe disease associated with sustained Th17 and regulatory T cells responses than Sporothrix schenckii sensu stricto in mice
(2018-01-01)
Little is known about the differences in the CD4+ T-cell response induced by Sporothrix schenckii and Sporothrix brasiliensis, the most virulent species that cause sporotrichosis. Here, the helper (Th) and regulatory T ...
Mecanismos de supresión de las células T reguladoras (Treg)
(Gaceta Médica de México. 2013;149 630, 2015)
T Regulatory cells from non-obese diabetic mice show low responsiveness to IL-2 stimulation and exhibit differential expression of anergy-related and ubiquitination factors
(Frontiers Media S.A., 2019-11)
Foxp3+ Regulatory T cells (Tregs) are pivotal for the maintenance of tolerance. Alterations in their number and/or function have been proposed to occur in the autoimmune-prone non-obese diabetic (NOD) mouse. Comparing the ...
Alloreactive regulatory T cells generated with retinoic acid prevent skin allograft rejection
(Wiley-Blackwell, 2015)
CD4+CD25+Foxp3+ regulatory T (Treg) cells mediate immunological self-tolerance and
suppress immune responses. Retinoic acid (RA), a natural metabolite of vitamin A, has
been reported to enhance the differentiation of ...
Participación de neuropilina-1 en la función inmune de células T reguladoras en la inducción de tolerancia a aloinjertos
(Universidad de Chile, 2020)
Las células T reguladoras (Tregs) disminuyen la respuesta inmune, y su principal
función es generar tolerancia hacia antígenos propios. Las células Tregs ejercen supresión a
través de distintos mecanismos que involucran ...
Role of the phenotypic and functional stability of regulatory T lymphocytes in the alveolar bone resorption during experimental periodontitis
(2020)
Periodontitis is a chronic inflammatory disease associated with the formation of dysbiotic plaque biofilms and characterized by the progressive destruction of the tooth‐supporting apparatus (periodontium). The alveolar ...
Combination Chemotherapy with Firocoxib Induces Reduction of Regulatory T Cells in Dogs with Multicentric B Cell Lymphoma
(Univ Agriculture, Fac Veterinary Science, 2019-01-01)
The aim of this study was to quantify T cells (CD4+, CD8+ and Treg), in dogs with multicentric lymphoma treated with a conventional CHOP protocol or with one in which firocoxib was used instead of prednisone. Twenty-one ...