Buscar
Mostrando ítems 11-20 de 3099
The inflammatory cytokine TNF contributes with RAC3-induced malignant transformation
(Univ Mainz-med Dept, 2018-11)
RAC3 is a coactivator of steroid receptors and NF-kB. It is usually overexpressed in several tumors, contributes to maintain cancer stem cells and also to induce them when is overexpressed in non-tumoral cells. In this ...
FARP1, ARHGEF39, and TIAM2 are essential receptor tyrosine kinase effectors for Rac1-dependent cell motility in human lung adenocarcinoma
(Elsevier, 2021-11)
Despite the undisputable role of the small GTPase Rac1 in the regulation of actin cytoskeleton reorganization, the Rac guanine-nucleotide exchange factors (Rac-GEFs) involved in Rac1-mediated motility and invasion in human ...
Proapoptotic and antiinvasive activity of Rac1 small molecule inhibitors on malignant glioma cells
(Dove Press, 2014-07)
Malignant gliomas are characterized by an intrinsic ability to invade diffusely throughout the normal brain tissue. This feature contributes mainly to the failure of existing therapies. Deregulation of small GTPases ...
Aβ1-42 stimulates actin polymerization in hippocampal neurons through Rac1 and Cdc42 Rho GTPases
(2007)
A number of psychiatric and neurodegenerative disorders, such as Alzheimer's disease, are characterized by abnormalities in the neuronal cytoskeleton. Here, we find that the enhancement in actin polymerization induced by ...
Crosstalk between rac1-mediated actin regulation and ros production
(2018)
The small RhoGTPase Rac1 is implicated in a variety of events related to actin cytoskeleton rearrangement. Remarkably, another event that is completely different from those related to actin regulation has the same relevance; ...
The Expression of RAC1 and Mineralocorticoid Pathway-Dependent Genes are Associated With Different Responses to Salt Intake
(2015)
Rac1 upregulation has been implicated in salt-sensitive hypertension as a modulator of mineralocorticoid receptor (MR) activity. Rac1 could affect the expression of oxidative stress markers, such as hemoxigenase-1 (HO1) ...
¿Es factible en Colombia la implementación de un sistema de integración aeronáutica basado en dirigibles híbridos?
A lo largo del documento veremos como las nuevas tecnologías en dirigibles híbridos pueden potencializar el desarrollo de las poblaciones más vulnerables del territorio Colombiano. El análisis está orientado a ver cómo ...
Study of the catalytic behavior of the homo- and copolymerization of 1-octadecene with the racemic metallocene catalysts rac-et(ind)(2)zrcl2 and rac-me2si(ind)(2)zrcl2.
(SOCIEDAD CHILENA DE QUIMICA, 1999)
Catalytic racemic metallocenes of othe type rac-X(Ind)(2)ZrCl2 (where X = union among indenyl rings, of the type -CH2-CH2-, (CH3)(2)Si- and (CH3)(2)C-, and Ind = indenyl) have shown a high catalytic activity for the ...
Regulation of Rho Family GTPases by Cell-Cell and Cell-Matrix Adhesion
(Sociedad de Biología de Chile, 2002)
Los riesgos en la seguridad operacional por la ausencia de despachadores de vuelo de helicópteros en Colombia
(Especialización en Administración AeronáuticaFacultad de Ciencias EconómicasUniversidad Militar Nueva Granada, 2020-10-25)
En los Reglamentos Aeronáuticos de Colombia (RAC) RAC 65, RAC 135 y RAC 141, se establecen los parámetros de entrenamiento para los despachadores de vuelo, referenciado únicamente para aviones. En Colombia, el transporte ...