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P-Glycoprotein contributes to cell membrane depolarization of hippocampus and neocortex in a model of repetitive seizures induced by pentylenetetrazole in rats
(Bentham Science Publishers, 2013-03)
P-glycoprotein (P-gp) has been associated with pharmacoresistance and mechanisms regulating the membrane potential. However, at present it is unknown if P-gp overexpression in brain is associated with changes in membrane ...
Ensaio pré-clínico do composto anticonvulsivante bromo-benzaldeído semicarbazona em ratos e cães
(Universidade Federal de Minas GeraisUFMG, 2007-09-14)
Despite the availability of wide range of anticonvulsant drugs, at least 25% of patients continue to have seizures. Furthermore, among those in whom seizures are effectively inhibited, substantial number of patients ...
Actividad anticonvulsivante y perfil toxicológico de nuevos derivados de pirimidinas
(anuario CDCH 2009, 2015)
Liberación in vitro de encefalinas durante la depresión postictal y la actividad interictal
(Instituto Nacional de Psiquiatría Ramón de la Fuente Muñiz, 1994)
The effects of pentylenetetrazol, chlordiazepoxide and caffeine in rats tested in the elevated plus-maze depend on the experimental illuminationLos efectos del pentilentetrazol, el clordiazepóxido y la cafeína en ratas probadas en el laberinto en cruz elevado dependen de la iluminación experimental
(Behavioural Brain Research, 2011)
The so-called anxiolytic and anxiogenic drugs are considered to cause, respectively, increases and
decreases in plus-maze open arm exploration, without modifying locomotor activity occurring in the
closed arms in an elevated ...