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Morphological evidences indicate that the interference of cimetidine on the peritubular components is responsible for detachment and apoptosis of Sertoli cells
(Biomed Central Ltd., 2008-05-09)
Cimetidine, referred as antiandrogenic agent, has caused alterations in the seminiferous tubules, including alterations in the peritubular tissue and death of myoid cells by apoptosis. Regarding the structural and functional ...
Dos capas independientes de miofilamentos constituyen el aparato contráctil de las células mioides peritubulares del testículo de rata
(Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica, 2015)
Biologia e nicho de espermatogônias tronco em catetos (tayassu tajacu) adultos
(Universidade Federal de Minas GeraisUFMG, 2011-08-19)
In the seminiferous epithelium, spermatogonial stem cells (SSCs) are located in a particular environment called niche that is controlled by the basement membrane, key testis somatic cells, and by factors emanating from the ...
The antineoplastic busulphan impairs peritubular and Leydig cells, and vitamin B-12 stimulates spermatogonia proliferation and prevents busulphan-induced germ cell death
(Elsevier B.V., 2017-11-01)
Busulphan (Bu), an alkylating agent used for bone marrow and spermatogonial stem cell transplantation (SSCT), impairs Sertoli (SC) cells, which are necessary for the spermatogonial stem cell (SSC) homing during transplantation. ...
Histological and Functional Organization in Human Testicle: Expression of Receptors c-kit and Androgens
(SOC CHILENA ANATOMIA, 2008-09)
The objective of this work was identify the presence of interstitial cells of Cajal, muscle cells, nerves and androgen
receptor positive cells in adult human testicle, using immunohistochemical detection for c-kit/CD-117, ...
Análise estereológica e funcional do testículo de rãs-touro (Lithobates catesbeianus) sexualmente maduras, com ênfase na cinética espermatogonial, proliferação e número de células de sertoli por cisto espermatogênico
(Universidade Federal de Minas GeraisUFMG, 2011-02-25)
Spermatogenesis is a complex and cyclic process that results in the daily production of millions of sperm. Although there are particularities among different species, this process seems to be very well conserved in the ...
Cimetidine-induced vascular cell apoptosis impairs testicular microvasculature in adult rats
(F Hernandez, 2012-10-01)
Cimetidine, an H-2 receptor antagonist used for treatment of gastric ulcers, exerts antiandrogenic and antiangiogenic effects. In the testes cimetidine impairs spermatogenesis, Sertoli cells and peritubular tissue, inducing ...
Histological and functional organization in human testicle: Expression of receptors c-kit and androgens Organización histológica y funcional en el testículo humano: Expresión de los receptores c-kit y andrógenos
(2008)
The objective of this work was identify the presence of interstitial cells of Cajal, muscle cells, nerves and androgen receptor positive cells in adult human testicle, using immunohistochemical detection for c-kit/CD-117, ...
Histological and Functional Organization in Human Testicle: Expression of Receptors c-kit and Androgens
(Sociedad Chilena de Anatomía, 2008)