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Expression Levels of Orexin Receptor 1 in Different stages of Colorectal Cancer
(2015)
Introduction: Orexin neuropeptides and their G-protein coupled receptors play essential roles in sleep-wake control, appetite/metabolism, stress, reward and others. OX1R is overexpressed in CRC, the activation by Orexin-A ...
Understanding the role of Orexin-A in advanced colorectal cancer.
(2016)
Introduction
Orexin-A (OXA) is a hypothalamic neuropeptide with various functions in central nervous system (CNS). Orexin receptors 1 (OX1R) and 2 (OX2R) are expressed in tissues different than CNS, including colorectal ...
Ghrelin and its interactions with growth hormone, leptin and orexins: implications for the sleep-wake cycle and metabolism
(Elsevier, 2014-02)
Several studies have shown that ghrelin administration promotes wakefulness in rodents, while in human males it induces sleep but has no effect in women. Ghrelin also plays an important role in metabolism and appetite ...
Participação da neurotransmissão orexinérgica nas respostas respiratórias à hipercarbia e hipóxia em sapos
(Universidade Federal de São CarlosBRUFSCarPrograma Interinstitucional de Pós-Graduação em Ciências Fisiológicas - PIPGCF, 2014-08-29)
The hypocretin or orexin A plays an important role in the modulation of respiratory control in mammals, but there are no data available for the role of Orexins in the peripheral and central chemoreception of non-mammalian ...
Role of the non-opioid dynorphin peptide des-Tyr-dynorphin (DYN-A(2-17)) in food intake and physical activity, and its interaction with orexin-A
(2016)
Food intake and physical activity are regulated by multiple neuropeptides, including orexin and dynorphin (DYN). Orexin-A (OXA) is one of two orexin peptides with robust roles in regulation of food intake and spontaneous ...