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Atropine reverses the antinociception of nonsteroidal anti-inflammatory drugs in the tail-flick test of mice
(2003)
The nonsteroidal anti-inflammatory drugs (NSAIDs) clonixin, diclofenac, piroxicam, ketoprofen, meloxicam, and paracetamol induced antinociception after intraperitoneal or intrathecal administration in mice submitted to an ...
The NSAIDs Indomethacin and Diflunisal as scavengers of photogenerated reactive oxygen species
(Wiley, 2013-06)
Diflunisal (DFNS) and Indomethacyn (IMTC) are two profusely employed NSAIDs that provide antiinflammatory and analgesic effects in humans. The scavenging of reactive oxygen species (ROS) by both NSAIDs was systematically ...
Curcumin conjugates of non‐steroidal anti‐inflammatory drugs: Synthesis, structures, anti‐proliferative assays, computational docking, and inflammatory response
(Wiley-VCH Verlag, 2020-08)
In an effort to combine the anti-proliferative effect of CUR-BF2 and CUR compounds with anti-inflammatory benefits of non-steroidal anti-inflammatory drugs (NSAIDs), a library of the bis- and mono-NSAID/CUR-BF2 and NSAID/CUR ...
Non-steroidal anti-inflammatory drugs may modulate the protease activity of Candida albicans
(Academic Press Ltd Elsevier B.V. Ltd, 2010-12-01)
The phenotypic pressure exerted by non-steroidal anti-inflammatory drugs (NSAIDs) on autochthonous and pathogenic microbiota remains sparsely known. In this study, we investigated if some NSAIDs increment or diminish the ...
Non-steroidal anti-inflammatory drugs may modulate the protease activity of Candida albicans
(Academic Press Ltd Elsevier B.V. Ltd, 2010-12-01)
The phenotypic pressure exerted by non-steroidal anti-inflammatory drugs (NSAIDs) on autochthonous and pathogenic microbiota remains sparsely known. In this study, we investigated if some NSAIDs increment or diminish the ...
Inhibition of mitochondrial complex i by various non-steroidal anti-inflammatory drugs and its protection by quercetin via a coenzyme Q-like action
(2012)
Mitochondrial dysfunction plays a major role in the development of oxidative stress and cytotoxicity induced by non-steroidal anti-inflammatory drugs (NSAIDs). A major objective of the present study was to investigate ...
Lack of effect of naltrexone on the spinal synergism between morphine and non steroidal anti-inflammatory drugs
(Polish Academy of Sciences, 2009)
To enhance analgesia, the combinatorial use of analgesic drugs with proven efficacies is a widely-used strategy to reduce adverse side effects. The present study characterizes the antinociceptive interaction of intrathecal ...
Carbachol interactions with nonsteroidal anti-inflammatory drugs
(2002)
The inhibition of cyclooxygenase enzymes by nonsteroidal anti-inflammatory drugs (NSAIDs) does not completely explain the antinociceptive efficacy of these agents. It is known that cholinergic agonists are antinociceptive, ...
Is it All Said for NSAIDs in Alzheimer's Disease? Role of Mitochondrial Calcium Uptake
(Bentham Science Publishers, 2018-04)
Epidemiological data suggest that non-steroidal anti-inflammatory drugs (NSAIDs) may protect against Alzheimer´s disease (AD). Unfortunately, recent trials have failed in providing compelling evidence of neuroprotection. ...