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Inibição sistêmica da NADPH oxidase: estudo do coração de ratos espontaneamente hipertensos com diabetes mellitus
(Universidade Estadual Paulista (Unesp), 2015-02-26)
Cardiovascular diseases (CVD) are the major cause of morbidity and mortality worldwide. Diabetes mellitus (DM) and arterial hypertension (AH) are the main risk factors for the development of CVD. The coexistence of diabetes ...
Association of NAD(P)H Oxidase with Glucose-Induced Insulin Secretion by Pancreatic beta-Cells
(ENDOCRINE SOC, 2009)
We previously described the presence of nicotinamide adenine dinucleotide phosphate reduced form [NAD(P)H] oxidase components in pancreatic beta-cells and its activation by glucose, palmitic acid, and proinflammatory ...
Association of NAD(P)H Oxidase with Glucose-Induced Insulin Secretion by Pancreatic beta-Cells
(Endocrine Soc, 2009-05-01)
We previously described the presence of nicotinamide adenine dinucleotide phosphate reduced form [NAD(P)H] oxidase components in pancreatic beta-cells and its activation by glucose, palmitic acid, and proinflammatory ...
NAD(P)H Oxidase Participates in the Palmitate-Induced Superoxide Production and Insulin Secretion by Rat Pancreatic Islets
(WILEY-BLACKWELL PUBLISHING, INC, 2011)
Nicotinamide adenine dinucleotide phosphate [NAD(P)H] oxidase complex has been shown to be involved in the process of glucose-stimulated insulin secretion (GSIS). In this study, we examined the effect of palmitic acid on ...
Efecto de clobenzorex y melatonina sobre la expresión génica y actividad enzimática de NADPH oxidasa y óxido nítrico sintasa en personas obesas
(2011-11-24)
Obesity is a chronic disease that is established by an imbalance between intake and energy expenditure, increases the risk of producing disorders such as insulin resistance and elevated cholesterol, which lead to the ...
Apocynin influence on oxidative stress and cardiac remodeling of spontaneously hypertensive rats with diabetes mellitus
(2016-09-01)
Purpose: Although increased oxidative stress is a major component of diabetic hypertensive cardiomyopathy, research into the effects of antioxidants on cardiac remodeling remains scarce. The actions of antioxidant apocynin ...
Influência de um complexo vitamínico (ácido ascórbico, alfa-tocoferol e beta-caroteno) no estresse oxidativo de células mononucleares de indivíduos não diabéticos e diabéticos tipo 1
(Universidade Federal de Minas GeraisUFMG, 2014-06-09)
Diabetic patients are exposed to increased oxidative stress due to several mechanisms, mainly hyperglycaemia. Pathological processes, such as those in type 1 diabetes, include diminished activity of the antioxidant defense ...
Exercise preconditioning of myocardial infarct size in dogs is triggered by calcium
(Lippincott Williams and Wilkins, 2015)
We showed that exercise induces early and late myocardial preconditioning in dogs and that these effects are mediated through nicotinamide adenine dinucleotide phosphate reduced form (NADPH) oxidase activation. As the ...
Inibição sistêmica da NADPH oxidase: estudo do coração de ratos espontaneamente hipertensos com diabetes mellitus
(Universidade Estadual Paulista (UNESP), 2016)