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Mostrando ítems 11-20 de 59
Biotransformação de corantes dispersos do tipo azo pela ação de enzimas redutoras e oxidação fotoeletrocatalítica após pré-concentração por MIP
(Universidade Estadual Paulista (Unesp), 2016-11-21)
Corantes sintéticos do tipo azo têm sido um assunto de grande preocupação ambiental devido ao potencial genotóxico e mutagênico dos produtos de biotransformação. Deste modo, nos últimos anos a consequência da ingestão ...
Biotransformação de corantes dispersos do tipo azo pela ação de enzimas redutoras e oxidação fotoeletrocatalítica após pré-concentração por MIPBiotransformation of disperse azo dyes by the action of reducing enzymes and photoelectrocatalytic oxidation after preconcentration by MIP
(Universidade Estadual Paulista (Unesp), 2016)
Benznidazole biotransformation in rat heart microsomal fraction without observable ultrastructural alterations: comparison to Nifurtimox-induced cardiac effects
(Fundação Oswaldo Cruz, 2008-09)
Benznidazole (Bz) and Nifurtimox (Nfx) have been used to treat Chagas’ disease. Recent studies evidenced cardiotoxic effects of Nfx. We attempted to test whether Bz behaves similarly. Bz reached heart tissue of male rats ...
The gene suicide system NTR/CB1954 causes ablation of differentiated 3T3L1 adipocytes by apoptosis
(Sociedad de Biología de Chile, 2004)
The azo dye Disperse Orange 1 induces DNA damage and cytotoxic effects but does not cause ecotoxic effects in Daphnia similis and Vibrio fischeri
(ELSEVIER SCIENCE BV, 2011)
Azo dyes constitute the largest group of colorants used in industry and can pass through municipal waste water plants nearly unchanged due to their resistance to aerobic treatment, which potentially exposes humans and local ...
Nitroreductive metabolic activation of some carcinogenic nitro heterocyclic food contaminants in rat mammary tissue cellular fractions
(Pergamon-Elsevier Science Ltd, 2009-01)
Several nitrofurans and nitroimidazoles have been widely used in veterinary medicine. Some of these compounds are breast carcinogens in rodents and their mechanism of action is hypothesized to be related to reactive ...
Benznidazole-induced ultrastructural and biochemical alterations in rat esophagus
(Elsevier Ireland, 2003-09)
Benznidazole (Bz) is a drug used in the chemotherapy of the acute and intermediate phases of Chagas’ disease (American Trypanosomiasis), an endemic parasitic disease afflicting more than 16 million people in Latin America. ...
Development and analysis of furazolidone-resistant Escherichia coli mutants
(John Wiley & Sons, Inc., 2015-06-15)
Furazolidone-resistant mutants were obtained from four clinical isolates of diarrhoeagenic Escherichia coli. The stability of the resistance and the frequency of mutation were established. The minimal inhibitory concentration ...
Novel 3‑Nitrotriazole-Based Amides and Carbinols as Bifunctional Antichagasic Agents
(Amer Chemical Soc, 2015)
3-Nitro-1H-1,2,4-triazole-based amides with a linear, rigid core and 3-nitrotriazole-based fluconazole analogues were synthesized as dual functioning antitrypanosomal agents. Such compounds are excellent substrates for ...