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Expression of NADPH oxidase in human pancreatic islets
(PERGAMON-ELSEVIER SCIENCE LTDOXFORD, 2012)
Aims: NADPH oxidase (NOX) is a known source of superoxide anions in phagocytic and non-phagocytic cells. In this study, the presence of this enzyme in human pancreatic islets and the importance of NADPH oxidase in human ...
Análisis de la localización, dinámica intracelular y producción de O2 - por el sistema NADPH oxidasa de las células fagocíticas
(Universidad de Antioquia, Facultad de MedicinaInmunodeficiencias PrimariasMedellín, Colombia, 2022)
Estudios de la explosión respiratoria y el sistema NADPH oxidasa en dos pacientes con sospecha clínica de una inmunodeficiencia en las células fagocíticas
(Universidad de Antioquia, Facultad de MedicinaInmunodeficiencias PrimariasMedellín, Colombia, 2022)
The oxidation of apocynin catalyzed by myeloperoxidase: Proposal for NADPH oxidase inhibition
(Elsevier B.V., 2007-01-15)
Apocynin has been used as an efficient inhibitor of the NADPH oxidase complex and its mechanism of inhibition is linked to prior activation through the action of peroxidascs. Here we studied the oxidation of apocynin ...
The oxidation of apocynin catalyzed by myeloperoxidase: Proposal for NADPH oxidase inhibition
(Elsevier B.V., 2007-01-15)
Apocynin has been used as an efficient inhibitor of the NADPH oxidase complex and its mechanism of inhibition is linked to prior activation through the action of peroxidascs. Here we studied the oxidation of apocynin ...
Islet NADPH oxidase activity modulates β-cell mass and endocrine function in rats with fructose-induced oxidative stress
(Elsevier Science, 2014-12)
Background: Islet NADPH oxidase activity is modulated by glucose and other insulin secretagogues and it might be part of the regulatory mechanism of insulin secretion. We studied its modulatory role of islet NADPH oxidase ...
Integration of TRPC6 and NADPH oxidase activation in lysophosphatidylcholine-induced TRPC5 externalization
(American Physiological Society, 2017-11)
Lipid oxidation products, including lysophosphatidylcholine (lysoPC), activate canonical transient receptor potential 6 (TRPC6) channels, and the subsequent increase in intracellular Ca2+ leads to TRPC5 activation. The ...
Influence of apocynin on cardiac remodeling in rats with streptozotocin-induced diabetes mellitus
(2018-01-17)
Background: Increased reactive oxygen species (ROS) generation in diabetes mellitus (DM) is an important mechanism leading to diabetic cardiomyopathy. Apocynin, a drug isolated from the herb Picrorhiza kurroa, is considered ...