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Exploiting the furo[2,3-b]pyridine core against multidrug-resistant Mycobacterium tuberculosis
(2019-04-15)
Identification of new antibiotics suitable for the treatment of tuberculosis is required. In addition to selectivity, it is necessary to find new antibiotics that are effective when the tuberculous mycobacteria are resistant ...
Effects of Brazilian green propolis extract on planktonic cells and biofilms of multidrug-resistant strains of Klebsiella pneumoniae and Pseudomonas aeruginosa
(2020-08-08)
Propolis could represent an alternative therapeutic agent for targeting multidrug-resistant bacteria due to its antimicrobial potential. The effect of Brazilian green propolis (BGP) aqueous extract (AqExt) was evaluated ...
Multidrug resistant tuberculosis
(BMJ Publishing Group, 2015)
Tuberculosis remains a major cause of morbidity and mortality globally, with an estimated nine million people developing the disease and 1.5 million deaths in 2013; equating to 4100 deaths a day.1 Nevertheless, considerable ...
Reported cases of multidrug-resistant tuberculosis and extensively drug-resistant tuberculosis in Salvador, Brazil
(Sociedade Brasileira de Medicina Tropical, 2017)
Acquisition of Multidrug-resistant Organisms in the Absence of Antimicrobials
(2018)
A nested case-control study among 137 nursing home residents who did not receive antimicrobials, of whom 44 acquired a multidrug-resistant organism, was performed. Risk factors for acquisition included gastrointestinal ...
Time to initiation of multidrug-resistant tuberculosis treatment and its relation with outcome in a high incidence district in Lima, Peru
(Wiley, 2015)
OBJECTIVE: To determine the time from diagnosis to start of multidrug resistant tuberculosis (MDR TB) treatment in Lima, Peru. METHODS: We studied new smear-positive TB adults that were started on MDR TB treatment or that ...
Weight variation over time and its relevance among multidrug-resistant tuberculosis patients
(Elsevier, 2014)
OBJECTIVES: We aimed to assess the variation in patient body weight over time according to the treatment outcome among multidrug-resistant tuberculosis (MDR-TB) cases. METHODS: This was a retrospective cohort study. The ...
Increased expression of the multidrug resistance-associated protein 1 (MRP1) in kidney glomeruli of streptozotocin-induced diabetic rats
(WALTER DE GRUYTER GMBH, 2011)
Oxidative stress has been linked to the podocytopathy, mesangial expansion and progression of diabetic nephropathy. The major cell defence mechanism against oxidative stress is reduced glutathione (GSH). Some ABC transporters ...