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Differential pulse adsorptive stripping voltammetric determination of methotrexate using a functionalized carbon nanotubes-modified glassy carbon electrode
(VersitaWarsaw, 2013-11)
A glassy carbon electrode (GC) containing multiwalled functionalized carbon nanotubes (MWCNTs) immobilized within a dihexadecylhydrogenphosphate film (DHP) is proposed as a nanostructured platform for determination of ...
Development and validation of a rapid reverse-phase HPLC method for the determination of methotrexate from nanostructured liquid crystalline systems
(2018-01-01)
A reversed-phase liquid chromatography (RP-LC) method was successfully developed and validated for the determination of methotrexate in nanostructured liquid crystalline systems composed by polyether functional siloxane ...
Impact of genetic polymorphism of metabolic pathway of methotrexate and survival rate of Mexican children will all [Impacto de polimorfismos genéticos de la vía metabólica del metotrexato sobre la sobrevida de niños Mexicanos con leucemia linfoblástica aguda (LLA)]
(UNIVERSIDAD DE ANTIOQUIA, 2015-01-01)
Background: Acute lymphoblastic leukemia (ALL) is a major cancer disease in Mexican pediatric population, were the genotype could affect the effectiveness of chemotherapy in which the methotrexate (MTX) is involved and ...
Optimized high performance liquid chromatography-ultraviolet detection method using core-shell particles for the therapeutic monitoring of methotrexate
(Xi'an Jiaotong University, 2016-04)
Methotrexate (MTX) is an antineoplastic drug, and due to its high toxicity, the therapeutic drug monitoring is strictly conducted in the clinical practice. The chemometric optimization and validation of a high performance ...
Time course effects of methotrexate on renal handling of water and electrolytes in rats. Role of aquaporin-2 and Na-K-2Cl-cotransporter
(Elsevier Ireland, 2019-09-01)
Methotrexate (MTX) is a derivate of folic acid, commonly used as an anchor drug for the treatment and management of malignant diseases and autoimmune disorders. However, nephrotoxicity is an important drawback of MTX ...
Efficacy of Methotrexate in Real-world Management of Giant Cell Arteritis: A Case-control Study
(2019)
Objective: To determine the effect of methotrexate (MTX) on relapse risk and glucocorticoid (GC) use in a large single-institution cohort of patients with giant cell arteritis (GCA).
Methods: Patients diagnosed with GCA ...
Development And Validation Of Hplc Method To Determination Of Methotrexate In Children Oncologic Patients
(VERDUCI PUBLISHERROME, 2015)