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Improvement of metabolic parameters and vascular function by metformin in obese non-diabetic rats
(PERGAMON-ELSEVIER SCIENCE LTDOXFORD, 2013-08-02)
Aims: Metformin is an insulin sensitizing agent with beneficial effects in diabetic patients on glycemic levels and in the cardiovascular system. We examined whether the metabolic changes and the vascular dysfunction in ...
Metformin pharmacokinetics in nondiabetic pregnant women with polycystic ovary syndrome
(SPRINGER HEIDELBERG, 2011)
The use of metformin throughout gestation by pregnant women with polycystic ovary syndrome (PCOS) significantly reduces the number of first trimester spontaneous abortions and the rate of occurrence of gestational diabetes. ...
Mechanisms involved in metformin action in the treatment of Polycystic Ovary Syndrome
(Bentham Science Publishers, 2009-12)
The N, N dimethyl-biguanide : Metformin is an antidiabetic drug that increases glucose utilization in insulinsensitive tissues. As Polycystic Ovary Syndrome (PCOS) and diabetes share some altered parameters-such as abnormal ...
Metformin during Pregnancy: Effects on Offspring Development and Metabolic Function
(2020-06-17)
Maternal obesity during pregnancy and gestational diabetes mellitus (GDM) are both associated with of several postnatal diseases in the offspring, including obesity, early onset hypertension, diabetes mellitus, and ...
Metformin during pregnancy: effects on offspring development and metabolic function
(Frontiers Media, 2020)
Maternal obesity during pregnancy and gestational diabetes mellitus (GDM) are both associated with of several postnatal diseases in the offspring, including obesity, early onset hypertension, diabetes mellitus, and ...
Neoadjuvant Metformin Added to Systemic Therapy Increases Pathological Complete Response in Breast Cancer: A Cross-sectional Study, Mexico Hospital, Costa Rica
(2018-02)
Background: Metformin shows anti-proliferative effect on tumor cells. We studied the effect of metformin on achieving complete pathological response (pCR) in breast cancer patients receiving neoadjuvant therapy in a Latin ...
Neoadjuvant Metformin Added to Systemic Therapy Increases Pathological Complete Response in Breast Cancer: A Cross-sectional Study, Mexico Hospital, Costa Rica
(2018-02)
Background: Metformin shows anti-proliferative effect on tumor cells. We studied the effect of metformin on achieving complete pathological response (pCR) in breast cancer patients receiving neoadjuvant therapy in a Latin ...
Metformin alleviates obesity and systemic oxidative stress in obese young swine
(2020)
The present study assessed the relationship between obesity induced by lifestyle and systemic oxidative stress and possible modulations by oral metformin treatments in young individuals, by using a translational swine model ...