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Modelling and determination of metabolic pools by stable carbon isotopes in the avian duodenal mucosa and albumen
(Journal of Animal Physiology and Animal Nutrition © 2015 Blackwell Verlag GmbH., 2015-05-09)
Stable isotope analyses have helped in assessing dietary switches if the diet undergoes metabolic alteration (isotopic exchange). However, when considering the effects over time of switching from one diet to another, one ...
A genetic toolkit for the analysis of metabolic changes in Drosophila provides new insights into metabolic responses to stress and malignant transformation
(Nature Publishing Group, 2019-12)
Regulation of the energetic metabolism occurs fundamentally at the cellular level, so analytical strategies must aim to attain single cell resolution to fully embrace its inherent complexity. We have developed methods to ...
Metabolic shift in the production of corrinoid compounds by Lactobacillus coryniformis in the absence of purines
(Elsevier France-editions Scientifiques Medicales Elsevier, 2020-01)
Lactobacillus coryniformis CRL 1001 and L. reuteri CRL 1098 have the complete genes necessary to synthesize pseudo-cobalamin as final product in a vitamin B12 free commercial medium. Unlike vitaminB12 (the most biologically ...
-α-synuclein overexpression triggers a lipid metabolic switch: lipid droplets as an early marker of neurodegeneration
(Sociedad Argentina de Investigación en Neurociencias, 2018)
Pathological accumulation of α-synuclein (α-syn) is a hallmark of Parkinson ‘s disease. α-syn is highly expressed in the brain and has the intriguing characteristic of interacting with lipids. However, little is known about ...
Mitochondrial dysfunction and the glycolytic switch induced by caveolin-1 phosphorylation promote cancer cell migration, invasion, and metastasis
(MDPI, 2022)
Simple Summary Caveolin-1 (CAV1) is a membrane protein that has been attributed a dual role in cancer, acting at early stages as a tumor suppressor and in later stages of the disease as a promoter of metastasis. In the ...
Nocturnal to Diurnal Switches with Spontaneous Suppression of Wheel-Running Behavior in a Subterranean Rodent
(Public Library of Science, 2015-10)
Several rodent species that are diurnal in the field become nocturnal in the lab. It has been suggested that the use of running-wheels in the lab might contribute to this timing switch. This proposition is based on studies ...