Buscar
Mostrando ítems 11-20 de 34
A new hybrid bacteriocin, Ent35–MccV, displays antimicrobial activity against pathogenic Gram-positive and Gram-negative bacteria
(Federation of European Biochemical Societies, 2012-01)
Bacteriocins and microcins are ribosomally synthesized antimicrobial peptides that are usually active against phylogenetically related bacteria. Thus, bacteriocins are active against Gram-positive while microcins are ...
Production of antibacterial peptide variants microcin J25 and its activity test in the Mycobacterium tuberculosis RNA polymerase
(Universidad Peruana Cayetano Heredia, 2019)
The success of rifampin as anti-tuberculosis therapy indicates that the inhibition of RNA polymerase (RNAP) of Mycobacterium tuberculosis (MtbRNAP) is an effective strategy, however, resistance to this antibiotic is ...
Inhibition of Salmonella enterica serovars by microcin J25
(Wiley Blackwell Publishing, Inc, 2004-07)
Escherichia coli microcin J25 (MccJ25) is a 2107-Da peptide antibiotic whose uptake into E. coli is mediated by the outer-membrane receptor FhuA and the inner membrane proteins TonB, ExbB, ExbD, and SbmA. A survey of the ...
Sensitization of microcin J25-resistant strains by a membrane-permeabilizing peptide
(American Society for Microbiology, 2010-10)
Microcin J25 (MccJ25) is a plasmid-encoded, 21-amino-acid, antibacterial peptide produced by Escherichia coli. MccJ25 inhibits RNA polymerase and the membrane respiratory chain. MccJ25 uptake into E. colisensitive strains ...
A membrane-permeabilizing peptide sensitizes microcin J25-resistant strains
(American Society for Microbiology, 2010-08)
Microcin J25 (MccJ25) is a plasmid-encoded, 21-amino-acid, antibacterial peptide produced by Escherichia coli. MccJ25 inhibits RNA polymerase and the membrane respiratory chain. MccJ25 uptake into E. colisensitive strains ...
The structure and biological aspects of peptide antibiotic microcin J25
(Bentham Science Publishers, 2009-03)
Microcin J25 (MccJ25) is a plasmid-encoded peptide of 21 L-amino acids (G1-G-A-G-H5-V-P-E-Y-F10-V-G- I-G-T15-P-I-S-F-Y20-G), excreted to the medium by an Escherichia coli strain. MccJ25 is active on Gram-negative bacteria ...
Tyrosine 9 is the key amino acid in microcin J25 superoxide overproduction
(Wiley Blackwell Publishing, Inc, 2009-11)
Escherichia coli microcin J25 (MccJ25) is a lasso-peptide antibiotic comprising 21 l-amino acid residues (G1-G-A-G-H5-V-P-E-Y- F10-V-G-I-G-T15-P-I-S-F-Y20-G). MccJ25 has two independent substrates: RNA-polymerase (RNAP) ...
Microcin E492 Amyloid Formation Is Retarded by Posttranslational Modification
(American Society for Microbiology, 2013)
Microcin E492, a channel-forming bacteriocin with the ability to form amyloid fibers, is exported as a mixture of two forms: unmodified
(inactive) and posttranslationally modified at the C terminus with a salmochelin-like ...
Structural characterization of microcin e492 amyloid formation: identification of the precursors
(ACADEMIC PRESS INC ELSEVIER SCIENCE, 2012)
The antibacterial action of microcin J25: evidence for disruption of cytoplasmic membrane energization in Salmonella newport
(Wiley Blackwell Publishing, Inc, 2001-11)
Microcin J25 (MccJ25) is a cyclic peptide of 21 unmodified amino acid residues produced by a fecal strain of Escherichia coli. It has previously been shown that the antibiotic activity of this peptide is mainly directed ...