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The activation of metabotropic glutamate 5 receptors in the rat ventral tegmental area increases dopamine extracellular levels
(2017)
The mesocorticolimbic circuit projects to the prefrontal cortex, hippocampus, amygdala, and nucleus accumbens, among others, and it originates in the dopaminergic neurons of the ventral tegmental area (VTA). The VTA receives ...
Glutamate metabotropic receptors in the lateral hypothalamus/perifornical area reduce the CO 2 chemoreflex
(2019-02-01)
It has been shown that the lateral hypothalamus/perifornical area (LH/PFA) exerts an important role on arousal-state variations of the central chemoreflex, but the mechanisms that underlie LH/PFA chemoreception are poorly ...
Effect of ionotropic and metabotropic glutamate agonists and D-aspartate on prolactin release from anterior pituitary cells
(Johann Ambrosius Barth Verlag Medizinverlage Heidelberg Gmbh, 2002-03)
Although the presence of ionotropic (iGluRs) and metabotropic (mGluRs) glutamate receptors has been demonstrated in the anterior pituitary, recent reports on the direct effect of glutamate on prolactin (PRL) secretion by ...
Amyloid-beta neurotoxicity and clearance are both regulated by glial group II metabotropic glutamate receptors
(Pergamon-Elsevier Science Ltd, 2017-09)
Astrocytes are now fully endorsed as key players in CNS functionality and plasticity. We recently showed that metabotropic glutamate receptor 3 (mGlu3R) activation by LY379268 promotes non-amyloidogenic cleavage of amyloid ...
Differential expression of cerebellar metabotropic glutamate receptors mGLUR2/3 and mGLUR4a after the administration of a convulsant drug and the adenosine analogue cyclopentyladenosine
(Springer/Plenum Publishers, 2007-07)
Metabotropic glutamate receptors (mGluR) play a role in synaptic transmission, neuronal modulation and plasticity but their action in epileptic activity is still controversial. On the other hand adenosine acts as a ...