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Control of membrane lipid homeostasis by lipid-bilayer associated sensors: A mechanism conserved from bacteria to humans
(Pergamon-Elsevier Science Ltd, 2019-10)
The lipid composition of biological membranes is key for cell viability. Nevertheless, and despite their central role in cell function, our understanding of membrane physiology continues to lag behind most other aspects ...
Differential expression of potassium channels in placentas from normal and pathological pregnancies: Targeting of the K ir 2.1 channel to lipid rafts
(2012)
Potassium channels play important physiological roles in human syncytiotrophoblasts (hSTBs) from placenta, an epithelium responsible for maternal-fetal exchange. Basal and apical plasma membranes differ in their lipid and ...
Localization of the Sodium-Taurocholate cotransporting polypeptide in membrane rafts and modulation of its activity by cholesterol in vitro
(ELSEVIER SCIENCE BV, 2008)
Background: The relevance of discrete localization of hepatobiliary transporters in specific membrane microdomains is not well known. Aim: To determine whether the Na+/taurocholate cotransporting polypeptide (Ntcp), the ...
L-ascorbic acid alkyl esters action on stratum corneum model membranes: an insight into the mechanism for enhanced skin permeation
(Elsevier Science, 2019-11)
L-ascorbic acid alkyl esters (ASCn) are lipophilic forms of vitamin C, which act as skin permeation enhancers. We investigated the physical changes induced by incorporating ASCn into stratum corneum (SC) lipid membranes ...
Disturbing Lipid Phase Equilibrium in Model Membrane Induced by Lytic Peptides
(2022-04-01)
Lytic peptides are rich in cationic and hydrophobic residues that form amphipathic α-helix when in contact with lipid bilayers. Evidence showed that they act on the lipidic phase of the cell membranes, inserting into the ...
Molecular interactions of an ornithine-rich pH-responsive self-Assembling peptide with a model lipid membrane: Conformational aspects
(2016-09-01)
Investigating interactions of designed peptide-based biomaterials with lipid membranes is important for applications in nanobiotechnology. Here the interaction of an ornithine-rich pH-responsive peptide called P11-5 with ...
Enrichment of canalicular membrane with cholesterol and sphingomyelin prevents bile salt-induced hepatic damage
(AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, 1999)
These studies were undertaken to characterize the role of plasma membrane cholesterol in canalicular secretory functions and hepatocyte integrity against intravenous taurocholate administration. Cholesterol and sphingomyelin ...
Membrane effects of Cocoa Procyanidins in Liposomes and Jurkat T Cells
(Sociedad de Biología de Chile, 2004)