Buscar
Mostrando ítems 11-20 de 894
Agonist mobility on supported lipid bilayers affects Fas mediated death response
(Elsevier Science, 2015-11-30)
Extrinsic apoptosis is initiated by recognition and clustering of the single-pass transmembrane proteins Fas ligand and Fas expressed at the surface of closely apposed lymphocytes and target cells, respectively. Since ...
Cholesterol modulates curcumin partitioning and membrane effects
(2018-01-01)
Curcumin, a polyphenol molecule, presents a wide range of biological activities as antioxidant, anticancer, anti-inflammatory, antimicrobial and wound healing. Although some strengths attributed to curcumin derive from ...
Partition of Amphiphilic Molecules to Lipid Bilayers by ITC: LowAffinity Solutes
(American Chemical Society, 2017-02)
A protocol is developed to allow the accurate characterization of partition to lipid bilayers for solutes with low affinity, using isothermal titration calorimetry. The methodology proposed is suitable for studies using ...
Lipid bilayer patterns fabrication by one-photon lithograpy
(Humana Press, 2017)
In the last decade, there has been an increasing interest in patterning surfaces with supported lipid bilayers. The ability of this system to control molecular composition and mobility of this system at micro- and nanoscales ...
Electrostatic interactions at the microscale modulate dynamics and distribution of lipids in bilayers
(Royal Society of Chemistry, 2017-02)
For decades, it has been assumed that electrostatic long-range (micron distances) repulsions in lipid bilayers are negligible due to screening from the aqueous milieu. This concept, mostly derived from theoretical calculations, ...
USE OF A NOVEL METHOD FOR DETERMINATION OF PARTITION-COEFFICIENTS TO COMPARE THE EFFECT OF LOCAL-ANESTHETICS ON MEMBRANE-STRUCTURE
(Elsevier Science BvAmsterdamHolanda, 1995)
Molecular dynamics study of uncharged bupivacaine enantiomers in phospholipid bilayers
(John Wiley & Sons Inc., 2012-09)
To investigate the effects of the uncharged bupivacaine (BVC) on the properties of model membranes of 1-palmitoyl- 2-oleoyl-sn-glycero-3-phosphatidylcholine (POPC), we have performed a series of molecular dynamics simulations. ...
Synergetic effect of silver nanoparticles and thiram on lipid bilayers
(2022-02-15)
The excessive concentration of nanomaterials and pesticides in industrial products, food, and in the environment can be a risk to human health. Exposure to these materials can occur through inhalation, dermal contact, or ...
Mechanical properties of binary DPPC/DPPS bilayers
(Royal Society of Chemistry, 2012-12-07)
In this work, we studied how the lipid composition and ionic strength of an aqueous solution affect the mechanical properties of the lipid bilayer. The interfacial tension, the bending modulus, the Gaussian curvature modulus ...