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Mostrando ítems 11-20 de 114
Ivermectin-loaded lipid nanocapsules: toward the development of a new antiparasitic delivery system for veterinary applications
(Springer, 2016-05)
Ivermectin (IVM) is probably one of the most widely used antiparasitic drugs worldwide, and its efficacy is well established. However, slight differences in formulation may change the plasma kinetics, the biodistribution, ...
Cystic echinococcosis therapy: Albendazole-loaded lipid nanocapsules enhance the oral bioavailability and efficacy in experimentally infected mice
(Elsevier Science, 2015-12)
Therapeutic failures attributed to medical management of cystic echinococcosis (CE) with albendazole (ABZ) have been primarily linked to the poor drug absorption rate resulting in low drug level in plasma and hydatid cysts. ...
Albendazole-lipid nanocapsules: Optimization, characterization and chemoprophylactic efficacy in mice infected with Echinococcus granulosus
(Academic Press Inc Elsevier Science, 2019-09)
Cystic echinococcosis (CE), which is caused during the metacestode larval stage of Echinococcus granulosus, is a life-threatening disease and is very difficult to treat. At present, the FDA-approved antihelmintic drugs are ...
Formulações inovadoras de base nanotecnológica para o tratamento tópico de micoses superficiais
(Universidade Federal de Santa MariaBrasilFarmacologiaUFSMPrograma de Pós-Graduação em Ciências FarmacêuticasCentro de Ciências da Saúde, 2016-02-19)
Superficial mycoses are fungal diseases caused on skin, hair and nails and are among the infectious
diseases with the highest incidence and difficult to treat, making them a serious public health problem. The
purpose of ...
Nanotechnological strategies for treatment of leishmaniasis-a review
(2017-02-01)
The World Health Organization (WHO) estimates that more than one billion people suffer from neglected tropical diseases. Leishmaniasis is a widespread disease, affecting 12 million people around the world with about 1-2 ...
Desenvolvimento de nanocápsulas contendo ditranol e sua incorporação em formulação semissólida de base aquosa
(Universidade Federal de Santa MariaBRFarmáciaUFSMPrograma de Pós-Graduação em Ciências Farmacêuticas, 2012-09-04)
Dithranol is very effective drug for the topical treatment of psoriasis. However, it has
some adverse effects, such as irritation and stain in the skin that difficult its application and
patient adherence to treatment. ...
Estudo toxicológico comparativo referente ao haloperidol na sua forma livre e nanoencapsulada
(Universidade Federal de Santa MariaBRFarmacologiaUFSMPrograma de Pós-Graduação em Farmacologia, 2015-08-14)
The association of haloperidol (HP) with polymeric nanocapsules causes a significant improve in therapeutic efficacy prolongs the drug time of action and reduces motor side effects in rats. However, in view of the HP ...
Secagem por aspersão de nanocápsulas de núcleo lipídico contendo tretinoína: desenvolvimento e incorporação em hidrogéis
(Universidade Federal de Santa MariaBRFarmáciaUFSMPrograma de Pós-Graduação em Ciências Farmacêuticas, 2010-12-07)
The aim of this work was to study the ability of lipid-core polymeric nanocapsules to protect tretinoin against UV degradation, even after their conversion to spray-dried powders and also to evaluate the feasibility of ...