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Characterization of myeloid or lymphoid acute leukemia by a chemiluminescence assay: Comparison with immunocytochemistry using an antimyeloperoxidase antibody
(1993-01-01)
A simple and sensitive chemiluminescence assay for the demonstration of the activity of intracellular myeloperoxidase (MPO) is described, which is useful for the distinction between myeloid and lymphoid commitment in blasts ...
Monoclonal B-cell lymphocytosis (MBL), CD4(+)/CD8(weak) T-cell large granular lymphocytic leukemia (T-LGL leukemia) and monoclonal gammopathy of unknown significance (MGUS): molecular and flow cytometry characterization of three concomitant hematological disorders
(HUMANA PRESS INCTOTOWA, 2012)
The diagnosis of T-cell large granular lymphocytic leukemia in association with other B-cell disorders is uncommon but not unknown. However, the concomitant presence of three hematological diseases is extraordinarily rare. ...
Antibody-targeted horseradish peroxidase associated with indole-3-acetic acid induces apoptosis in vitro in hematological malignancies
(Pergamon-Elsevier B.V. Ltd, 2011-05-01)
Indole-3-acetic acid (IAA), when oxidized by horseradish peroxidase (HRP), is transformed into cytotoxic molecules capable of inducing cell injury. The aim of this study was to test if, by targeting hematopoietic tumors ...
T-cell large granular lymphocytic leukemia: treatment experience with fludarabine
(HOSPITAL CLINICAS, UNIV SAO PAULOSÃO PAULO, 2012-07)
OBJECTIVES: The aim of this retrospective study was to investigate the results of T-cell large granular lymphocytic leukemia treatment with fludarabine by assessing the complete hematologic response, the complete molecular ...
Using wavelet sub-band and fuzzy 2-partition entropy to segment chronic lymphocytic leukemia images
(2018-03-01)
Histological images analysis is an important procedure to diagnose different types of cancer. One of them is the chronic lymphocytic leukemia (CLL), which can be identified by applying image segmentation techniques. This ...
A rare case of Acute Lymphocytic Leukemia (ALL) presenting with double Philadelphia chromosome: relapse or secondary leukemia?
(Sociedade Brasileira de Genética, 2003-01-01)
The Philadelphia chromosome is observed in 5% of pediatric acute lymphocytic leukemia (ALL) and in 25% to 50% of adult ALL cases, and is associated with poor prognosis. Double Ph in a hyperdiploid karyotype is common in ...
Neglected players: Tumor associated neutrophils involvement in chronic lymphocytic leukemia progression
(Impact Journals, 2019-03)
The old paradigm that establishes that neutrophils are just short half-life cells committed to kill bacteria in situ at early stages of infection is changing. Nowadays, there are plenty of reports that focus on neutrophils ...
Bullous leukemia cutis mimicking facial cellulitis
(2016-03-01)
Bullous leukemia cutis is an uncommon clinical manifestation of cutaneous infiltration by leukemic cells, from B-cell chronic lymphocytic leukemia. We present the case of a 67-year-old, female, chronic lymphocytic leukemia ...