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Níveis séricos de adiponectina e de leptina durante a gravidez de adolescentes - curva gestacional
(Universidade Federal de São Paulo (UNIFESP), 2019-05-30)
Introduction: Adiponectin and leptin have a characteristic pattern and play important roles during pregnancy in adult women, however little is known about these molecules during pregnancy in adolescents. Objective: To ...
Hyperleptinemia in obese adolescents deregulates neuropeptides during weight loss
(Elsevier B.V., 2011-07-01)
Leptin has emerged over the past decade as a key hormone not only in energy balance regulation but also in neuroendocrine and inflammatory processes. the aim of the present study was to evaluate whether hyperleptinemia ...
Relationship of serum adipocyte-derived proteins with insulin sensitivity and reproductive features in pre-pubertal and pubertal daughters of polycystic ovary syndrome women
(Elsevier, 2012)
Objective: To evaluate in a cross-sectional study adiponectin and leptin levels in prepubertal and pubertal
daughters of women with PCOS and their relationship to insulin sensitivity and reproductive features.
Study ...
Mechanisms linking childhood weight status to metabolic risk in adolescence
(Wiley, 2020)
Background Obesity is a risk factor for insulin resistance (IR) and metabolic disease. Objective To examine potential metabolic pathways linking childhood weight status to adolescent IR and metabolic risk. Methods Participants ...
Avaliação do papel da obesidade e de adipocinas como fatores de risco de Tromboembolismo Venoso: um estudo de casocontrole
(Universidade Federal de São Paulo (UNIFESP), 2019-03-18)
Introduction: The venous thromboembolism (VTE) is a frequent disease related to a relevant morbimortality. The association between obesity and VTE is particularly important due the increased prevalence of obesity in the ...
Influence of skeletal muscle mass and fat mass on the metabolic and inflammatory profile in sarcopenic and non-sarcopenic overfat elderly
(2018-01-01)
Background: Sarcopenic elderly present low muscle mass and strength, however, it is not clear if the inflammatory and metabolic profile is more related to low lean mass or high fat mass in sarcopenic and non-sarcopenic ...
The role of free fatty acids in the inflammatory and cardiometabolic profile in adolescents with metabolic syndrome engaged in interdisciplinary therapy
(Elsevier Science Inc, 2016)
The purpose of the present study was to evaluate if interdisciplinary therapy can influence the cardiometabolic and serum free fatty acid profile. The second aim was to evaluate if there is an association between serum ...
Enlarged adipocytes in subcutaneous adipose tissue associated to hyperandrogenism and visceral adipose tissue volume in women with polycystic ovary syndrome
(2018)
Context Polycystic ovary syndrome (PCOS) is an androgen excess disorder associated with obesity and adipose tissue disturbances. Our aim was to evaluate gene expression of adipocytokines and adipocyte characteristics in ...
Plasma obestatin concentrations are negatively correlated with body mass index, insulin resistance index, and plasma leptin concentrations in obesity and anorexia nervosa
(ELSEVIER SCIENCE INC, 2008)
Background: Obestatin is a recently identified ghrelin gene product that was reported to inhibit appetite and gastric motility in contrast to ghrelin. We investigated fasting obestatin and ghrelin levels in patients with ...
Plasma lactate and leukocyte mitochondrial DNA copy number as biomarkers of insulin sensitivity in non-diabetic women
(2019)
High plasma lactate levels have been associated with reduced mitochondrial respiratory capacity and increased type 2 diabetes risk, while mitochondrial DNA (mtDNA) copy number has been proposed as a biomarker of mitochondrial ...