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The Drosophila insulin-degrading enzyme restricts growth by modulating the PI3K pathway in a cell-autonomous manner
(2014)
Mammalian insulin-degrading enzyme (IDE) cleaves insulin, among other peptidic
substrates, but its function in insulin signaling is elusive. We use the Drosophila system to define the function of IDE in the regulation of ...
I-Insulin transfer to mitochondria
(Springer, 2014-10)
The aim of this study was to determine if insulin is transferred to mitoplasts by insulin-degrading enzyme (IDE).Hepatic mitochondria were isolated and controlled by electron microscopy. IDE was obtained from rats muscle ...
Lacking Of Estradiol Reduces Insulin Exocytosis From Pancreatic Beta-cells And Increases Hepatic Insulin Degradation
(Elsevier Science INCNew York, 2016)
The catalytic domain of insulin-degrading enzyme forms a denaturant-resistant complex with amyloid β peptide: Implications for Alzheimer disease pathogenesis
(American Society for Biochemistry and Molecular Biology, 2008-06)
Insulin-degrading enzyme (IDE) is central to the turnover of insulin and degrades amyloid β (Aβ) in the mammalian brain. Biochemical and genetic data support the notion that IDE may play a role in late onset Alzheimer ...
Endurance Training Inhibits Insulin Clearance And Ide Expression In Swiss Mice
(PUBLIC LIBRARY SCIENCESAN FRANCISCO, 2015)
The Drosophila insulin degrading enzyme restricts growth by modulating the PI3K pathway in a cell autonomous manner.
(2014)
Mammalian insulin-degrading enzyme (IDE) cleaves insulin, among other peptidic substrates, but its function in insulin signaling is elusive. We use the Drosophila system to define the function of IDE in the regulation of ...
The Drosophila insulin degrading enzyme restricts growth by modulating the PI3K pathway in a cell autonomous manner.
(2014)
Mammalian insulin-degrading enzyme (IDE) cleaves insulin, among other peptidic substrates, but its function in insulin signaling is elusive. We use the Drosophila system to define the function of IDE in the regulation of ...
Acute Exercise Restores Insulin Clearance In Diet-induced Obese Mice
(BIOSCIENTIFICA LTDBRISTOL, 2016)
Acute Exercise Restores Insulin Clearance In Diet-induced Obese Mice
(Bioscientifica LtdBristol, 2016)