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Selective effect of INGAP-PP upon mouse embryonic stem cell differentiation toward islet cells
(Elsevier Science, 2009-02)
We evaluated the effect of islet neogenesis-associated protein pentadecapeptide (INGAP-PP) upon islet β- and non-β cell differentiation from mouse embryonic stem (mES) cells. ES-D3 cell lines were cultured following ...
Progesterone induces apoptosis of insulin-secreting cells: insights into the molecular mechanism
(Bioscientifica Ltd, 2014-05-01)
Progesterone has been associated with the development of gestational diabetes (GD) due to the enhancement of insulin resistance. As b-cell apoptosis participates in type 1 and type 2 diabetes pathophysiology, we proposed ...
MODULATION OF EARLY STEPS IN INSULIN ACTION IN THE LIVER AND MUSCLE OF EPINEPHRINE TREATED RATS
(Humana Press IncTotowa, 1995)
Ebselen and cytokine-induced nitric oxide synthase expression in insulin-producing cells
(1996-12-13)
Interleukin-1 (IL-1) may be a mediator of β-cell damage in insulin-dependent diabetes mellitus (IDDM). The IL-1 mechanism of action on insulin-producing cells probably includes activation of the transcription nuclear factor ...
Ebselen and cytokine-induced nitric oxide synthase expression in insulin-producing cells
(1996-12-13)
Interleukin-1 (IL-1) may be a mediator of β-cell damage in insulin-dependent diabetes mellitus (IDDM). The IL-1 mechanism of action on insulin-producing cells probably includes activation of the transcription nuclear factor ...
IGF-I and insulin induce different intracellular calcium signals in skeletal muscle cells
(SOC ENDOCRINOLOGY, 2004-08)
We studied the effect of IGF-I and insulin on intracellular Ca2+ in primary cultured myotubes. IGF-I induced a fast and transient Ca2+ increase, measured as fluo-3 fluorescence. This response was blocked by both genistein ...