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Iron Deficiency and IL1β Polymorphisms in Helicobacter pylori-infected Children
(Blackwell Publishing Ltd, 2016)
© 2016 John Wiley & Sons Ltd.Background: Helicobacter pylori infection has been associated with an imbalance of iron homeostasis. IL-1β has been related with iron absorption disturbances through a variety of mechanisms. ...
Memory consolidation impairment induced by Interleukin-1β is associated with changes in hippocampal structural plasticity
(Elsevier Science, 2019-09)
Pro-inflammatory cytokines, particularly Interleukin-1β (IL-1β), can affect cognitive processes such as learning and memory. The aim of this study was to establish whether the effect of IL-1β on contextual fear memory is ...
Epiregulin (EREG) is upregulated through an IL‐1β autocrine loop in Caco‐2 epithelial cells with reduced CFTR function
(Wiley-liss, Div John Wiley & Sons Inc, 2017-11)
CFTR is a cAMP-regulated chloride channel, whose mutations produce cystic fibrosis. The impairment of CFTR activity increases the intracellular Cl- concentration, which in turn produces an increased interleukin-1β (IL-1β) ...
Effects of Interleukin-1β in Glycinergic Transmission at the Central Amygdala
(Frontiers Media S.A., 2021-03)
Interleukin-1β (IL-1β) is an important cytokine that modulates peripheral and central pain sensitization at the spinal level. Among its effects, it increases spinal cord excitability by reducing inhibitory Glycinergic and ...
CFTR modulates RPS27 gene expression using chloride anion as signaling effector
(Elsevier Science Inc, 2017-09)
In Cystic Fibrosis (CF), the impairment of the CFTR channel activity leads to a variety of alterations, including differential gene expression. However, the CFTR signaling mechanisms remain unclear. Recently, culturing ...
IL-1β reduces GluA1 phosphorylation and its surface expression during memory reconsolidation and α-melanocyte-stimulating hormone can modulate these effects
(Pergamon-Elsevier Science Ltd, 2018-01)
Pro-inflammatory cytokines can affect cognitive processes such as learning and memory. Particularly, interleukin-1β (IL-1β) influences hippocampus-dependent memories. We previously reported that administration of IL-1β in ...
Intracellular chloride concentration changes modulate IL-1β expression and secretion in human bronchial epithelial cultured cells
(Wiley, 2017)
Abstract: Cystic fibrosis (CF) is caused by mutations in the CFTR gene, which encodes a cAMP-regulated chloride channel. Several cellular functions are altered in CF cells. However, it is not clear how the CFTR failure ...
Autophagy mediates Interleukin-1beta secretion in human neutrophils
(Frontiers Media S.A., 2018-02)
Interleukin-1β (IL-1β), a major proinflammatory cytokine, is a leaderless cytosolic protein whose secretion does not follow the classical endoplasmic reticulum-to-Golgi pathway, and for which a canonical mechanism of ...
Differential inflammasome expression and IL-1β secretion in monocyte-derived dendritic cells differentiated with IL-4 or IFN-α
(BioMed CentralLondres, 2013-12-27)
NLRP3-inflammasome activation was evaluated in monocyte-derived dendritic cells (DC) obtained through IL-4 (IL4-DC) or IFN-α (IFN-DC) protocols and pulsed with chemically inactivated HIV-1. Inflammasome' genes expression ...
Evaluation of mediators IL-1α, IL-1β and TNF-α, in crevicular gingival fluid of patients with periodontitisEvaluación de los mediadores IL-1α, IL-1β y TNF-α, en fluido gingival crevicular de pacientes con periodontitis
(Universidad Nacional Mayor de San Marcos, Facultad de Odontología, 2019)