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Boosting the suppressive effects of Ascaris suum components in IFN-γ-deficient mice
(Sociedade Brasileira de Medicina Tropical - SBMT, 2009)
High molecular weight components from Ascaris suum extract suppress ovalbumin-specific immunity in mice. In IFN-γ-deficient mice, ovalbumin-specific delayed-type hypersensitivity reactions are more strongly downregulated ...
Obtención de anticuerpos recombinantes anti-IFN-alfa2b destinados a uso terapéutico humano
(2012-02-28)
La expresión endógena aumentada de IFN alfa se asocia a numerosas desórdenes inflamatorios y enfermedades autoinmunes donde la citoquina puede ser un factor en el inicio o en el mantenimiento de la patología. En la actualidad, ...
Type I IFN deficiency: an immunological characteristic of severe COVID-19 patients
Recently, a paper published in Science by Hadjadj et al. reported
that type I interferon (IFN) deficiency, could be a hallmark of
severe coronavirus disease 2019 (COVID-19) caused by severe
acute respiratory syndrome ...
Propolis: lymphocyte proliferation and IFN-gamma production
(Elsevier B.V., 2003-07-01)
We evaluated propolis influence on polyclonal activation of lymphocytes by concanavalin A (Con A). The in vitro experiments showed that propolis decreases splenocyte proliferation both in the absence or presence of Con A. ...
Propolis: lymphocyte proliferation and IFN-gamma production
(Elsevier B.V., 2003-07-01)
We evaluated propolis influence on polyclonal activation of lymphocytes by concanavalin A (Con A). The in vitro experiments showed that propolis decreases splenocyte proliferation both in the absence or presence of Con A. ...
Papel do IFN-y e do óxido nítrico na patogênese do dengue experimental em camundongos
(Universidade Federal de Minas GeraisUFMG, 2007-08-03)
Dengue is currently the most important mosquito-borne disease that affects humans and constitutes a serious world health problem. Although knowledge about the disease pathogenesis is incipient, an important role is attributed ...