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Oxoisoaporphines: Regioselective deuterium labelling involving the metastable hydrogenated photoproduct anions
(2011)
During the 1H NMR study of the photoreduction of aza-oxoisoaporphines, aza-OIAs, (7H-benzo[e]perimidin-7-ones) by amines we found an unexpected H/D isotopic exchange in the aromatic positions 4 and 6 of these molecules. ...
Intrinsically Disordered Regions of the DNABinding Domain of Human FoxP1 Facilitate Domain Swapping
(Elsevier, 2020)
Forkhead box P (FoxP) proteins are unique transcription factors that spatiotemporally regulate gene expression by
tethering two chromosome loci together via functional domain-swapped dimers formed through their ...
Definitions of terms relating to mass spectrometry (IUPAC Recommendations 2013)
(Int Union Pure Applied ChemistryRes Triangle PkEUA, 2013)
Hydrogen/deuterium exchange mass spectrometry for characterizing phosphoenolpyruvate-induced structural transitions in Mycobacterium tuberculosis 5-enolpyruvylshikimate-3-phosphate synthase (EC 2.5.1.1)
(Elsevier B.V., 2011-04-30)
The enzyme 5-enolpyruvylshikimate-3-phosphate synthase (EPSPS) catalyzes the reaction between shikimate-3-phosphate (S3P) and phosphoenolpyruvate (PEP) to form 5-enolpyruvylshikimate-3-phosphate, an intermediate in the ...
Hydrogen/deuterium exchange mass spectrometry for characterizing phosphoenolpyruvate-induced structural transitions in Mycobacterium tuberculosis 5-enolpyruvylshikimate-3-phosphate synthase (EC 2.5.1.1)
(Elsevier B.V., 2011-04-30)
The enzyme 5-enolpyruvylshikimate-3-phosphate synthase (EPSPS) catalyzes the reaction between shikimate-3-phosphate (S3P) and phosphoenolpyruvate (PEP) to form 5-enolpyruvylshikimate-3-phosphate, an intermediate in the ...
Molecular dynamics simulations provide atomistic insight into hydrogen exchange mass spectrometry experiments
(American Chemical Society, 2013-01)
It is now clear that proteins are flexible entities that in solution switch between conformations to achieve their function. Hydrogen/Deuterium Exchange Mass Spectrometry (HX/MS) is an invaluable tool to understand dynamic ...
Dynamics of glyphosate-induced conformational changes of Mycobacterium tuberculosis 5-enolpyruvylshikimate-3-phosphate synthase (EC 2.5.1.19) determined by hydrogen-deuterium exchange and electrospray mass spectrometry
(Amer Chemical Soc, 2008-07-15)
The enzyme 5-enolpyruvylshikimate-3-phosphate synthase (EPSPS) catalyzes the reaction between shikimate 3-phosphate and phosphoenolpyruvate to form 5-enolpyruvylshikimate 3-phosphate, an intermediate in the shikimate ...