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Effects of heme oxygenase isozymes on Leydig cells steroidogenesis
(BioScientifica, 2009-10)
In the present study, we demonstrate the expression of heme oxygenase (HO) isozymes, HO-1 and HO-2 (listed as HMOX1 and HMOX2 in the MGI Database), in MA-10 Leydig tumor cells and its effect on steroidogenesis. The well-known ...
Heme Oxygenase-1 (HO-1) Expression in Prostate Cancer Cells Modulates the Oxidative Response in Bone Cells.
(Public Library Science, 2013-11-04)
Prostate cancer (PCa) is a leading cause of death among males. It is currently estimated that inflammatory responses are linked to 15-20% of all deaths from cancer worldwide. PCa is dominated by complications arising from ...
Nuclear Heme oxygenase-1 is associated to tumor progression in Human Head and Neck Carcinoma.
(Academic Press Inc Elsevier Science, 2012-10)
The expression of heme oxygenase-1 (HO-1) was shown to be increased in multiple tumors compared with their surrounding healthy tissues and was also observed to be up-regulated in oral squamous cell carcinomas (OSCC). ...
Naturally derived heme-oxygenase 1 inducers and their therapeutic application to immune-mediated diseases
(Frontiers Media S.A., 2020)
Heme oxygenase (HO) is the primary antioxidant enzyme involved in heme group degradation. A variety of stimuli triggers the expression of the inducible HO-1 isoform, which is modulated by its substrate and cellular stressors. ...
The heme oxygenase-carbon monoxide system in the regulation of cardiorespiratory function at high altitude
(2012)
Pulmonary arterial hypertension is one of the most serious pathologies that can affect the 140 million people living at altitudes over 2500. m. The primary emphasis of this review is pulmonary artery hypertension in mammals ...
Heme Oxygenase-1 protects astroglia against manganese-induced oxidative injury by regulating mitochondrial quality control
(Elsevier Ireland, 2018-10)
Heme Oxygenase-1 (HO-1), a stress- responsive enzyme which catalyzes heme degradation into iron, carbon monoxide, and biliverdin, exerts a neuroprotective role involving many different signaling pathways. In Parkinson ...
Pharmacological Inhibition of Host Heme Oxygenase-1 Suppresses Mycobacterium tuberculosis Infection In Vivo by a Mechanism Dependent on T Lymphocytes
(American Society for Microbiology, 2017)